nonhomologous


Also found in: Dictionary.

nonhomologous

(of chromosomes or chromosomal segments) containing different genes not pairing during meiosis. Compare HOMOLOGOUS CHROMOSOMES.
References in periodicals archive ?
Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination.
A nonhomologous DNA fragment (BamHI:EcoRl fragment of v-erbB) was first amplified with composite primers constituted by the c-erbB-2 primer sequence attached to a short, 20-nucleotide stretch of sequence (provided by the supplier) designed to hybridize to opposite strands of the heterologous DNA fragment.
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
While this could presumably happen with fetuses of either gender, it's easiest to detect by looking at long term (i.e., years) postpartum mothers of male offspring with a molecular test for cells bearing holandric markers (ones from the nonhomologous part of the Y chromosome) and most studies have focused on this easily discernable group.
For H7, emergence of HP viruses is attributed to nonhomologous recombination resulting in simultaneous insertion of several amino acids at the HA cleavage site.
However, rearrangements of the acrocentric chromosomes can result in nonhomologous ROB [e.g., rob (13q14q)] or homologous rearrangements [e.g., rob (21q21q)].
Conversely, high levels of DNA-PKcs, a key player in nonhomologous end joining, accelerated the radiotherapy induced DSB repair mechanism [63].
The nonhomologous end-joining (NHEJ) pathway is the default method of repair, introducing insertions and deletions (INDELs) that normally will result in a nonfunctional genetic product [69].
Anti-Ro/SSA antibodies represent two distinct entities of autoantibodies that react with two nonhomologous proteins, Ro52/TRIM21 and Ro60/TROVE2, respectively, a cytoplasmatic nuclear protein [30].
LpxI is a nonhomologous alternative to LpxH present in some Gram-negative bacteria that lack LpxH and LpxG, particularly [alpha]-proteobacteria [17, 54].