nonesterified fatty acids
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Related to nonesterified fatty acids: Free fatty acids
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This leads to upregulation of the fatty acid translocase, CD36, and an increased uptake of nonesterified fatty acids (NEFA) into hepatocytes causing ectopic fat deposition and oxidative stress in the liver.
The aim of this study was to investigate the effects of different levels of forage and concentrates diets on the metabolism of glucose AY-hydroxybutyrate (BOHB) and nonesterified fatty acid (NEFA) in livers of nonlactating goats.
Technical note: an improved method to quantify nonesterified fatty acids in bovine plasma.
These chapters go into detailed descriptions of the methods and clinical significance of measuring the traditional lipid risk factors (e.g., total cholesterol, triglycerides, HDL-cholesterol, and LDL-cholesterol) and the less traditional, more novel, and potentially relevant measurements of apolipoproteins, lipoprotein(a), lipid peroxidation, lipases, cholesterol ester transfer protein, lecithin:cholesterol acyl transferase, phospholipids, nonesterified fatty acids, triglyceride-rich lipoprotein remnants, and LDL receptors.
Albumin is added to the free hormone assay reagent by a number of manufacturers to buffer the effects of increased nonesterified fatty acids that develop in serum in vitro.
To place these important observations in context, we wish to comment on the following: (a) the relevance of cascade effects in influencing the unbound concentrations of numerous other drugs such as aspirin and nonsteroidal antiinflammatory agents; (b) the importance of a similar cascade effect as a mechanism that can increase free thyroid hormone concentrations; and (c) the potential to overestimate the in vivo importance of apparent serum concentrations of nonesterified fatty acids (NEFAs) as direct or indirect inhibitors of hormone or drug binding.
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