nondepolarizing agent

nondepolarizing agent

Anesthesiology An agent–eg, pancuronium, used to facilitate airway management, control alveolar ventilation, abolish motor reflexes, and provide muscle relaxation for surgery. See Pancuronium, Pipercuronium, Vecuronium. Cf Depolarizing agent.
References in periodicals archive ?
The nondepolarizing agents are poorly lipophilic and do not penetrate well into fat tissue or across the blood-brain barrier.
All nondepolarizing agents have a tendency to release histamine from mast cells.
By preventing the binding of acetylcholine, the nondepolarizing agents block the depolarizing effects of acetylcholine, thereby preventing muscle contraction.