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Related to nonapeptide: Oligopeptide


An oligopeptide containing nine amino acyl residues (for example, oxytocin).
References in periodicals archive ?
(14) A quantitative measure of thymic function is achieved by assaying the nonapeptide hormone thymulin produced by thymic epithelial cells.
Serologic assay based on g/iadrnre/ated nonapeptides as a highly sensitive and specific diagnostic aid in celiac disease.
Sometimes oxytocin is referred to as a nonapeptide, since nona means "nine."
The product is the immunodominant nonapeptide derived from the extracellular domain of the HER2 protein for therapeutic intervention in breast carcinoma.
The nonapeptide [BK.sub.9], whose amino acid sequence RPPGFSPFR remains identical in the human and mouse genomes, enlarges blood vessels and causes the blood pressure to decrease as a result.
Thymic peptide thymulin, which is a metallopeptide consisting of a nonapeptide (Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asp) that couples with zinc ions, mostly has inhibitory effects on immune responses [12, 31] and also stimulates endocrine systems, indicating its role in the recovery from inflammatory conditions [32].
Of these naturally occurring lactotripeptides, IPP seems to be by far the most potent--about twice as effective in vitro compared with VPP Interestingly, IPP was discovered as part of a nonapeptide in snake venom, which actually led to the first antihypertensive ACE inhibiting drug, Captopril, in 1982.
In addition, there are a wide range of permeabilizers such as polycationic polymyxin B nonapeptide, which interact with and disorganize the anionic LPS thereby sensitizing the bacteria to hydrophobic antibiotics (Vaara and Vaara, 1983a, b).
A nonapeptide derived from stannin containing the sequence Cys-Trp-Cys was able to dealkylate TMT, followed by binding of the resulting DMT.
Within the RAS, ACE-2 competes with ACE because it is capable of hydrolyzing the inactive decapeptide angiotensin I (AngI) into the nonapeptide Ang(1-9), thus decreasing the amount of Ang I available for pressor AngII generation by ACE.