antiinflammatory drug

(redirected from non-steroidal antiinflammatory drug)

antiinflammatory drug 

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.
References in periodicals archive ?
THIS non-steroidal antiinflammatory drug (NSAID) works by targeting and reducing the production of prostaglandins, hormone-like chemicals responsible for inflammation, pain and fever.
Flunixin Non-steroidal antiinflammatory drug. Targets inflamed tissue, counteracts the effects of trauma, also used for colic and muscle pain.
3 Careful with painkillers Diclofenac, a non-steroidal antiinflammatory drug, like ibuprofen, has been linked to a 40 per cent increased risk of heart attack and stroke, according to a study by Barts and the London School of Medicine and Dentistry.
A non-steroidal antiinflammatory drug (indomethacin), will quell the inflammation around the joint quickly, and a 'cage' over the affected foot will stop bedclothes irritating it.
Researchers at the University of California, San Francisco, looked at five-year survival rates for people diagnosed with the disease and found the regular use of non-steroidal antiinflammatory drugs (NSAIDs), such aspirin and ibuprofen, significantly improved survival for a third or more of patients with the disease.
They found that regular use of non-steroidal antiinflammatory drugs (NSAIDs), such as aspirin and ibuprofen, significantly improved survival for a third or more of patients with head and neck cancer.
Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal antiinflammatory drugs increase the risk of atherothrombosis?
Non-selective non-steroidal antiinflammatory drugs (NSAIDs) such as ibuprofen could increase the risk of being admitted to hospital with the heart problem, a study found.
Trends in prescribing gastroprotective agents with non-steroidal antiinflammatory drugs in an orthopaedic outpatient unit of a Tertiary Care Hospital.

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