non-steroidal anti-inflammatory drugs


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non-steroidal anti-inflammatory drugs

A range of drugs with painkilling and inflammation-reducing properties that act by inhibiting the enzyme cyclo-oxygenase that converts the fatty acid arachidonic acid to PROSTAGLANDINS. The latter are a common cause of pain and the inhibition of their production relieves pain, but prostaglandins also have desirable effects, hence some of the unwanted side-effects of NSAIDs. Long-term use of these drugs has been found to be associated with a reduced incidence of oral cancer but with an increased risk of death from cardiovascular disease. The range of NSAIDs includes ASPIRIN, BENORYLATE (benorilate), DIFLUNISAL, FENBUFEN, FENOPROFEN, IBUPROFEN, NAPROXEN, DICLOFENAC, INDOMETHACIN (indometacin), PHENLYBUTAZONE and PIROXICAM.

Non-steroidal anti-inflammatory drugs (NSAIDs)

Aspirin, ibuprofen, naproxen, and many others.
Mentioned in: Mastocytosis
References in periodicals archive ?
Cardiovascular risk needs to be taken into account when prescribing any non-steroidal anti-inflammatory drug.
Dr Kerry Kuehl, a sports medicine specialist at the university, said: "Our research suggests that tart cherry juice may work like common non-steroidal anti-inflammatory drugs, used by millions to treat pain and inflammation after exercise.
The task force concluded that increased risk for stroke, intestinal bleeding or kidney failure from taking more than 300 mg daily of aspirin or non-steroidal anti-inflammatory drugs outweighed the possible benefits of colorectal cancer prevention.
Previous studies had suggested that the medicines, called non-steroidal anti-inflammatory drugs (NSAIDs), could help prevent several types of cancer.
The first two issues include feature articles and regular columns on such topics as side effects of non-steroidal anti-inflammatory drugs, facilitating better patient/provider relationships, misperceptions about osteoarthritis, alternative therapies for chronic pain, HIPAA compliance and treating rheumatoid arthritis.
18 FDA Regulatory actions for the COX-2 Selective and Non-Selective Non-Steroidal Anti-inflammatory drugs.
The scientists found during interviews that the study volunteers without cancer were about twice as likely as the cancer patients to have regularly used non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, during the previous 6 months.
Two popular non-steroidal anti-inflammatory drugs (NSAIDs) failed to slow dementia in a study of 351 patients with mild-to-moderate Alzheimer's disease.
Prostaglandins may be involved in the physiologic response to exercise; some data suggests a lower risk of bleeding in runners taking non-steroidal anti-inflammatory drugs (NSAIDS).
Risk of hyponatremia is higher among females, runners using non-steroidal anti-inflammatory drugs (like aspirin or ibuprofen), and runners who finish in four hours or more.
At least 20 elderly people in Birmingham die from stomach bleeds caused by non-steroidal anti-inflammatory drugs (NSAIDS) each year, according to Dr Whittington.

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