non-steroidal anti-inflammatory drugs

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non-steroidal anti-inflammatory drugs

A range of drugs with painkilling and inflammation-reducing properties that act by inhibiting the enzyme cyclo-oxygenase that converts the fatty acid arachidonic acid to PROSTAGLANDINS. The latter are a common cause of pain and the inhibition of their production relieves pain, but prostaglandins also have desirable effects, hence some of the unwanted side-effects of NSAIDs. Long-term use of these drugs has been found to be associated with a reduced incidence of oral cancer but with an increased risk of death from cardiovascular disease. The range of NSAIDs includes ASPIRIN, BENORYLATE (benorilate), DIFLUNISAL, FENBUFEN, FENOPROFEN, IBUPROFEN, NAPROXEN, DICLOFENAC, INDOMETHACIN (indometacin), PHENLYBUTAZONE and PIROXICAM.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Non-steroidal anti-inflammatory drugs (NSAIDs)

Aspirin, ibuprofen, naproxen, and many others.
Mentioned in: Mastocytosis
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
According to the company, Vimovo is a fixed-dose combination tablet of naproxen, a pain-relieving non-steroidal anti-inflammatory drug (NSAID) and esomeprazole, the same gastroprotective active ingredient as in Nexium.
Since the completion of the current study, the SZWH has developed a clinical guideline for the use of non-steroidal anti-inflammatory drug suppositories in the management of post-partum pain, indicating careful use of these drugs in women with hypovolaemia, pre-eclampsia, gastrointestinal bleeding or ulceration, asthma, allergies to aspirin or other non-steroidal anti-inflammatory drugs or haematological conditions associated with prolonged bleeding time.20 There appears to be a clear advantage in using non-steroidal anti-inflammatory drug suppositories to provide short-term pain relief for perineal pain after childbirth.
Current treatment of BME includes the use of steroidal and non-steroidal anti-inflammatory drugs, which can have serious side effects.
Non-steroidal anti-inflammatory drugs (NSAIDs) comprise a group of medicines that exert their action by inhibiting cyclooxygenase (COX) isozymes.
The link between taking aspirin, and similar medications called non-steroidal anti-inflammatory drugs (NSAIDS), and bowel (colorectal) cancer prevention is well established, the article states.
In the case of arthritis patients, it was found that as compared to non-steroidal anti-inflammatory drugs they preferred homeopathic pills such as Rustox which eliminated acidity and managed pain better.
Naproxen is the active ingredient in Aleve and some other non-steroidal anti-inflammatory drugs (NSAIDs).
A new study presented at the Annual Congress of the European League Against Rheumatism in July suggests that one in eight patients at risk of developing a serious adverse drug event (ADE) is taking over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs), often to treat a musculoskeletal complaint such as arthritis.
Higher-dose use of some non-steroidal anti-inflammatory drugs, such as diclofenac and ibuprofen, ups the likelihood of having a heart attack or a stroke, a study found.
London, May 30 ( ANI ): A group of most commonly used drugs known as non-steroidal anti-inflammatory drugs (NSAIDs) can increase long-term users' heart-attack risk by more than a third, a study has shown.
Non-steroidal anti-inflammatory drugs (NSAID), such as celecoxib, act as COX-[epsilon] inhibitors and are widely used for osteoarthritis.

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