(9) At week 12, LDL cholesterol levels were reduced from baseline by 60%, non-HDL cholesterol
by 55%, total cholesterol by 38%, total triglycerides by 23%, and lipoprotein (a) by 31%.
Remnant cholesterol was estimated by the simple subtraction of LDL cholesterol from non-HDL cholesterol
. As anticipated, those patients with higher pretreatment triglyceride levels and therefore higher levels of pretreatment remnant cholesterol had a greater decrease in remnant cholesterol after treatment than patients with relatively normal pretreatment triglyceride and remnant levels.
Mean Non-HDL Cholesterol
levels were 141.4 mg/dL with a standard deviation of 43 mg/dL.
However, it is observed that elevations in total cholesterol levels resulted from elevated HDL levels when the comparison was repeated after calculating non-HDL cholesterol
Female (n = 20) Male (n = 20) Fasting blood 87,7 [+ or -] 14,2 82,8 [+ or -] 10,5 glucose (mg/dL) Total cholesterol 212,7 [+ or -] 53,1 171,9 [+ or -] 27,1 (mg/dL) HDL-cholesterol 49,6 [+ or -] 14,6 39,0 [+ or -] 14,6 (mg/dL) Triglycerides 206,8 [+ or -] 123,6 190,9 [+ or -] 68,1 (mg/dL) LDL-cholesterol 121,7 [+ or -] 43,0 94,7 [+ or -] 26,4 (mg/dL) Non-HDL cholesterol
163,1 [+ or -] 50,8 132,9 [+ or -] 31,8 (mg/dL) p value Fasting blood 0,1828 glucose (mg/dL) Total cholesterol 0,0037 (mg/dL) HDL-cholesterol 0,9970 (mg/dL) Triglycerides 0,0128 (mg/dL) LDL-cholesterol 0,0394 (mg/dL) Non-HDL cholesterol
0,0468 (mg/dL) HDL: high density lipoprotein; LDL: low density lipoprotein; mg/dL: milligrams per deciliter.
Clinical relevance of non-HDL cholesterol
in patients with diabetes.
However, total cholesterol, LDL cholesterol, triglycerides, non-HDL cholesterol
, fasting insulin, HOMA-IR, GOT and Lipid Accumulation Product decreased more significantly in the nutraceutical group versus placebo.
And after 16 weeks, the patients supplementing with pantethine experienced reductions from baseline in total cholesterol of 6%, in LDL of 11%, and non-HDL cholesterol
The researchers also found that the total cholesterol, triglycerides, small dense LDL, non-HDL cholesterol
and other blood measurements of the subjects were also good.
It tests simultaneously a lipid profile, including total cholesterol, HDL cholesterol and triglycerides, as well as glucose, and also measures LDL, TC/HDL ratio, LDL/HDL ratio and non-HDL cholesterol
The non-HDL cholesterol
levels were determined by the difference between the total cholesterol and HDL levels.
The study compared the effects of corn and extra virgin olive oil on LDL cholesterol (primary outcome variable), total cholesterol, HDL cholesterol (good cholesterol), Non-HDL cholesterol
, Triglycerides and the total to HDL cholesterol ratio.