Detection of hepatitis G virus RNA in patients with acute non-A-E hepatitis
. J Viral Hepat 1998; 5 : 161-4.
Of 459 patients who underwent heart transplantation at the hospital between 1983 and 1992, 140 developed posttransplant hepatitis: hepatitis B infection (HBV) - 69; hepatitis C infection (HCV) - 49; HBV/HCV coinfection - 11; non-A-E hepatitis
The patients included in this study were: 45 patients with a diagnosis of non-A-E hepatitis
, 116 patients with hepatitis C, 100 patients with hepatitis A, and 100 patients with hepatitis B.
Approximately 5%-20% of cases of acute and chronic hepatitis cannot be attributed to any known virus. This form of hepatitis has been termed "hepatitis X" or "hepatitis non-A-E." According to the CDC, 26%-29% of patients with acute non-A-E develop chronic hepatitis. Recently, researchers cloned four viruses that are candidates for the causative agents of non-A-E hepatitis
: hepatitis G (HGV) and hepatitis GBV, which includes GBV-A, GBV-B, and GBV-C.