non-A, non-B hepatitis


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non-A, non-B hep·a·ti·tis

hepatitis caused by any number of infectious agents not detectable by methods that reveal the presence of hepatitis viruses A and B.
Synonym(s): NANB hepatitis

non-A, non-B hepatitis

(nŏn-ā′ nŏn-bē′)
n.
Any of various forms of hepatitis, including hepatitis C and hepatitis E, caused by a virus that is antigenically different from hepatitis viruses A and B.

non-A, non-B hepatitis

A group of hepatitides which are the major cause of transfusion-related hepatitis Incidence 7/105/yr–US Risk factors 42% IV drug abuse, 40% unknown risk factors, 6% sexual contact, 6% blood transfusion, 3% household contact, 2% health care professional; of the ±150,000 new cases/yr–US, 30-50% become chronic carriers–20% of these develop cirrhosis; NANBH may also be enteric–parenteral; NANBH is most commonly due to HCV and enteric NANBH to HEV Management IFN-α2b results in significant histologic reversal and serum ALA response Prognosis No ↑ in overall mortality with chronic NANBH, but ↑ liver-related deaths. See Hepatitis.

non-A, non-B hep·a·ti·tis

(NANB) (hep'ă-tī'tis)
Hepatitis caused by any number of infectious agents not detectable by methods that reveal the presence of hepatitis viruses A and B.
References in periodicals archive ?
Failure to detect chronic liver disease after epidemic non-A, non-B hepatitis.
This "library" of bacteriophage-expressed polypeptides was subsequently screened against the serum of a patient with documented chronic non-A, non-B hepatitis.
and colleagues at the NIH Clinical Center ultimately provided the link between the bacteriophage-expressed polypeptide, the antibody that reacted to it, and non-A, non-B hepatitis.
Harvey Alter and colleagues assessed the value of ALT and anti-HBc as surrogate markers for non-A, non-B hepatitis (now hepatitis C).
Harvey Alter of NIH), and associates at the CDC studied 140 patients who had non-A, non-B hepatitis.
Statistical analysis subsequently revealed that the factors associated with increased risk of non-A, non-B hepatitis included a lower level of education, household or sexual activity with a person who had had hepatitis within the previous year, and heterosexual activity with more than two partners.
Gambino related that 50 per cent of acute cases of non-A, non-B hepatitis become chronic.
Hepatitis B virus antibody in blood donors and the occurence of non-A, non-B hepatitis in transfusion recipients: An analysis of the transfusion-transmitted viruses study.
Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis, N.
High levels of ALT indicate liver injury and provide today's sole criterion for diagnosing non-A, non-B hepatitis, Vyas says.
So, although these 68 individuals would have been misdiagnosed with non-A, non-B hepatitis, their blood would not have been transfused.
Scientists have known for two decades that several agents can cause non-A, non-B hepatitis.