Torg-Winchester syndrome(redirected from nodulosis-arthropathy-osteolysis syndrome)
Torg-Winchester syndromeAn autosomal recessive syndrome (OMIM:259600) characterised by generalised osteolysis and osteopenia, coarse face, corneal opacities, patches of thickened, hyperpigmented skin, hypertrichosis and gingival hypertrophy.
TWS is caused by mutation of MMP2 on chromosome 16q13-q21, which encodes matrix metalloproteinase 2.
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