nodularin

nodularin

hepatoxic cyclic pentapeptide from Nodularia spumigena.
Mentioned in ?
References in periodicals archive ?
Inhibition of protein phosphatases by microcystis and nodularin associated with hepatotoxicity.
Growth, nitrogen fixation, and nodularin production by two Baltic Sea cyanobacteria.
Indeed, the evidence that microcystin is a potent tumor promoter and that nodularin (another cynanobacterial hepatotoxin) is a liver carcinogen in rat liver (Ohta et al.
microcystin or nodularin, which are toxins of blue-green algae) (11,12).
Blooms can affect the water quality, as indicated by changes in pH, transparency, and biodiversity, and produce a variety of toxins including microcystin, nodularin, and ana-toxina.
Nodularia spumigena has been found responsible for the toxicity of the blooms and the toxin involved has been nodularin, a hepatotoxic cyclic pentapeptide (Anon.
Production and specificity of monoclonal antibodies against nodularin conjugated through N-methyldehydrobutyrine.
Several PP1 and PP2A inhibitors, such as okadaic acid, nodularin, and microcystin-LR, are classified as tumor promoters (Fujiki and Suganuma 1999).
Pure MC-LR and nodularin can be oxidized within seconds to minutes (Rositano et al.
In vitro and in vive effects of protein phosphatase inhibitors, microcystin and nodularin, on mouse skin and fibroblasts.
Microcystins and nodularin, toxins produced by cyanobacteria that are present in eutrophic water, have been linked to liver and other cancers.
The antibodies used in the assay were most specific for MCYST-LR (100%) and arginine--arginine variant (MCYST-RR; 126%), with some cross-reactivity with tyrosine--arginine variant (MCYST-YR; 65%) and nodularin (48%) (16).