Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
primary cutaneous melanoma that presents as rapidly growing smoothly spheroid or ulcerated nodules in which tumor cells microscopically invade the dermis beneath all the lateral epidermal margins of involvement.
a melanoma that is nodular and uniformly pigmented, usually bluish-black, and sometimes surrounded by an irregular halo of pale, unpigmented skin. The lesion is always raised and may be dome-shaped or polypoid. Most often the tumor is found in middle-aged adults and occurs in 10% to 15% of patients with melanoma. See also lentigo maligna melanoma, superficial spreading melanoma.
nodular melanomaThe most aggressive of all melanomas, which arises de novo in the so-called vertical growth phase—i.e., it is invasive ab initio. Nodular melanomas comprise 15% of all melanomas.
50% average 5-year survival.