nodular goiter


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Related to nodular goiter: multinodular goiter, nodular goitre, toxic nodular goiter

nodular goiter

Etymology: L, nodus, knot; Gk, guttur, throat
an enlarged goiter that contains nodules.
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Nodular goiter

nodular goiter

A goiter that contains nodules.
See also: goiter

Nodular goiter

An enlargement of the thyroid (goiter) caused when groups of cells collect to form nodules.

goiter, goitre

enlargement of the thyroid gland, causing a swelling in the front part of the neck.

adenomatous goiter
multilobular goiters cause thyroid enlargement in cats.
colloid goiter
is characterized by the presence of a large soft thyroid gland with its glandular space distended with colloid. Most cases occur in neonatal lambs, calves and kids which show a high rate of stillbirths and weakness and a high mortality rate. Enlarged thyroid glands and alopecia are good indicants of the existence of a nutritional deficiency of iodine, the usual cause of goiter in animals.
dyshormonogenetic goiter
an impairment in thyroglobulin synthesis is thought to be the cause of inherited, congenital goiter recorded in sheep, cattle and goats. The thyroid gland is enlarged, there is a high neonatal mortality, a silky wool in sheep and a rough, sparse haircoat in goats. Called also inherited goiter.
goitrogen-induced goiter
there are a number of goitrogens in the environment of grazing animals. Their effect is almost entirely on the newborn. Common agents are low level intakes of cyanogenetic glycosides, e.g. in white clover, the glucosinolates in Brassica spp. plants, and mimosine in Leucaena leucocephala.
hyperplastic goiter
diffuse hyperplasia is the standard response to dietary iodine deficiency and to poisoning by plant goitrogens. It may also be caused by persistent exposure of the fetus to a high iodine intake of the dam. See also iodide goiter (below). Neonates are the usual subjects and the disease is manifested by clinical goiter, often sufficient to cause dystocia, and weak neonates with a high rate of stillbirths and deaths soon after birth.
inherited goiter
see dyshormonogenetic goiter (above).
iodide goiter
that occurring in reaction to iodides at high concentrations, due to inhibition of iodide organification.
nodular goiter
an endocrinologically inactive nodular enlargement of the thyroids in old dogs and horses. In old cats similar goiters sometimes develop functional adenomas.
References in periodicals archive ?
Cure rate was 77% in patients with Graves' disease group and 85% in toxic nodular goiter group (p=0.
Fine-Needle Aspirate (FNA) Diagnoses Using Conventional Criteria and Follow-up Histopathologic Diagnoses FNA Diagnosis (n) Surgical Follow-up (n) Hurthle cell neoplasm (13) Hurthle cell adenoma (6) Hurthle cell carcinoma (3) Hashimoto's thyroiditis (4) Nonneoplastic thyroid (17) Hurthle cell carcinoma (1) Hashimoto's thyroiditis (12) Nodular goiter (4)
The Wagner and Seiler (29) study showed that thyroid carcinoma, Graves disease, thyroiditis and recurrent goiter have a 3 or 4 times greater risk of nerve damage than that for euthyroid nodular goiter and adenoma.
Health monitoring of individuals exposed to EBDCs should include checking for thyroid gland disorders, particularly nodular goiters.
Colloidal nodule, lymphocytic thyroiditis, nodular goiter and nodular hyperplasia were accepted as benign cytology.
Matos-Santos A, Nobre EL, Costa JG, et al: Relationship between the number and impact of stressful life events and the onset of Graves' disease and toxic nodular goiter.
Diagnosis of GD was based on the presence of clinical and biochemical thyrotoxicosis [suppressed thyrotropin (TSH) and/or elevated free tri-iodothyronine (FT3) and/or free thyroxine (FT4) and positive TSH receptor antibody (TRAb)], diffuse or nodular goiter, and increased radioactive iodine (RAI) uptake.
19) They found that patients with nodular goiter and elevated thyroid auto-antibody levels were significantly more likely to become hypothyroid following unilateral thyroid lobectomy (p < 0.
Studies have shown that the TRAb test has the highest diagnostic power to differentiate Graves' disease from toxic nodular goiters.
Factors known to precipitate thyroid storm are infection, surgery, trauma, radioactive iodine treatment in patients with toxic nodular goiters, pregnancy, anticholinergic and adrenergic drugs, thyroid hormone ingestion, and diabetic ketoacidosis (American Association of Clinical Endocrinologists [AACE], 2002).

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