nodular fasciitis


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Related to nodular fasciitis: fibromatosis, myositis ossificans

fasciitis

 [fas″e-i´tis]
inflammation of a fascia.
necrotizing fasciitis a fulminating group A streptococcal infection beginning with severe or extensive cellulitis that spreads to involve the superficial and deep fascia, producing thrombosis of the subcutaneous vessels and gangrene of the underlying tissues. A cutaneous lesion usually serves as a portal of entry for the infection, but sometimes no such lesion is found.
nodular fasciitis (proliferative fasciitis) a benign, reactive proliferation of fibroblasts in the subcutaneous tissues and commonly associated with the deep fascia.
pseudosarcomatous fasciitis a benign soft tissue tumor occurring subcutaneously and sometimes arising from deep muscle and fascia.

nod·u·lar fas·ci·i·tis

a rapidly growing tumorlike proliferation of fibroblasts, not thought to be neoplastic, with mild inflammatory exudation occurring in fascia; the fibrosis may infiltrate surrounding tissue but does not progress indefinitely or metastasize.

nodular fasciitis

A benign, rapidly growing reactive proliferation of fibroblasts in the deep dermis/subcutis on the arms, trunk, or neck of young adults (mean age 34), usually measuring < 3 cm. 

DiffDx
Dermatofibroma, DFSP, other fasciitides (fibroma of tendon sheath, intravascular, parosteal), fibromatosis, fibrosarcoma, fibrous histiocytoma, inflammatory myofibroblastic tumour, leiomyosarcoma, myxoid tumours, spindle-cell sarcoma.
References in periodicals archive ?
Nodular fasciitis of the breast is a rare and reactive process composed of fibroblasts and myofibroblasts.
Schwannoma Similar to Positive: Neurofibroma but Neurofilament, S100 characteristic Verocay Bodies with nuclear palisading, Antoni A & B areas Nodular Fasciitis Fibroblasts with Positive: SMA, vesicular nuclei in vimentin, Negative: myxoid stroma.
Nodular fasciitis. Its morphologic spectrum and immunohistochemical profile.
Histologic analysis established a diagnosis of nodular fasciitis (figure 3).
The differential diagnosis of myofibroma includes nodular fasciitis, leiomyoma, FH, and myopericytoma.
Nodular fasciitis is a benign lesion first described by Konwaler in 1955 when he called it pseudosarcomatous fasciitis.
Nodular fasciitis is a proliferative lesion containing fibroblasts and myofibroblasts in myxoid stroma.
Nodular fasciitis is an uncommon tumor-like fibroblastic proliferation of the head and neck that is difficult to differentiate from its more malignant counterparts.
Exuberant, extensive scars, reactive spindle cell nodules, and nodular fasciitis are reactive entities that may mimic FLSCC.
The differential diagnosis for infantile myofibromatosis includes other types of fibromatosis, congenital infantile fibrosarcoma, infantile hemangiopericytoma, inflammatory myofibroblastic tumors, fibrohistiocytic tumors with a predominantly fibrous pattern, smooth muscle tumors such as leiomyomas and leiomyosarcomas, neurogenic tumors such as neurofibromas and low-grade malignant peripheral nerve sheath tumors, and nodular fasciitis.
Other cutaneous and subcutaneous lesions that are considered in the differential diagnosis include leiomyoma, hemangiopericytoma, fibrous hamartoma of infancy, cutaneous inflammatory pseudotumor, desmoid tumor, nodular fasciitis, plexiform fibrohistioeytic tumor, neurofibroma, and dermatomyofibroma.
Other breast lesions that may exhibit myxoid features include myxoid stromal change, myxoid fibroadenoma, myxoid nerve sheath tumors, myxoid dermatofibrosarcoma protuberans, myxomas, and myxoid foci in nodular fasciitis. Heterologous elements such as bone formation can be seen in the breast in hamartomas, calcified fibroadenoma, and osseous metaplasia in benign mesenchymal lesions such as lipoma or leiomyoma and in malignant lesions such as phyllodes tumor, metaplastic spindle cell carcinoma, matrix-producing carcinoma, sarcomas, and malignant adenomyoepithelioma with osteogenic differentiation.

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