nociceptors


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Related to nociceptors: Pacinian corpuscle, Gate control theory

nociceptors

Nerve endings selectively responding to painful stimuli. Stimulation of nociceptors causes the sensation of pain.

nociceptors (nōˈ·si·sepˑ·ters),

n.pl a group of cells that acts as a receptor for painful stimuli. Minor stress from a mechanical, chemical, thermal, or any other damaging stimulus may prime these cells.
References in periodicals archive ?
The more we can understand about how these nociceptors work," he says, "the more likely we are to have treatments for the vast numbers of people with chronic pain conditions.
An attractive aspect of targeting nociceptors is that this approach would be most effective when inflammation is already present and should accelerate its resolution," says Clifford Woolf, MD, PhD, director of the F.
They concluded that in these C-fiber nociceptors the TREK2 keeps membrane potentials more negative, stabilizing their membrane potential, reducing firing and thus limiting the amount of spontaneous burning pain.
Cold-induced vasospasm after finger replantation; abnormal sensory regeneration and sensitisation of cold nociceptors.
At the very least, painful input due to exertion from nociceptors may reduce an athlete's motivation to continue.
An over-stimulated nervous system makes extra nociceptors, and it doesn't take much for them to holler, "Ouch
PNP is mediated through nociceptors, which are specialised nerve endings, which become spontaneously active (or hyperactive) or hypersensitive after lesion or disease.
Postoperative pain results not only from local tissue injury, leading to spontaneous firing of nociceptors and their increased sensitivity to stimuli (primary hyperalgesia), but also from central nervous system changes resulting in sensitisation and pain from a wider area (secondary hyperalgesia) (11).
Nociceptors convert the stimuli (which can be mechanical, thermal, or chemical) to electrical signals {transduction), which trigger action potentials.
Besides, the activity of M2 receptors located on peripheral nociceptors of the skin has also been reported (Bernardini et al.
Persistent headache, due to stimulation of (trigeminal) nociceptors in the expanding arterial walls is almost invariably present.
Nociceptive pain: results from thermal, chemical, or mechanical tissue damage that activates nociceptors (pain receptors) in the body