nociceptive impulse

nociceptive impulse

(nō″sĭ-sĕp′tĭv)
Impulse giving rise to sensations of pain.
References in periodicals archive ?
Dexamethasone, a steroid with anti-inflammatory properties block the nociceptive impulse transmission along the unmyelinated C fibres (11) and suppressing ectopic neuronal discharge.
So the early phase of the formalin test represents the transmission of nociceptive impulses, while late phase is associated with the development of a delayed inflammatory response.
Modulation, which takes place primarily in the dorsal horn, is the stage in which nociceptive impulses are amplified or inhibited.
Transduction: This is the phase at which afferent nerve endings translate the energy from noxious stimuli into nociceptive impulses.
Transmission: During this stage, the nociceptive impulses are conveyed from the peripheral site of injury to the dorsal horn of the spinal cord and from there to the brain.
Modulation: This is the process by which the nociceptive impulses are either inhibited or amplified, with input from both the ascending and descending pathways.
The translation of noxious stimuli into nociceptive impulses
The phase in which nociceptive impulses are conveyed from the site of injury to the dorsal horn of the spine and then to the brain
In humans, the mechanism of the latter was suggested to be the result of alpha-2 adrenoreceptor proliferation at the site of nerve damage and reduced transmission of nociceptive impulses and prevention or lessening of spinal cord sensitization when these receptors are activated.