Ali T, Chakraburtty A, Mahmood S, Bronze MS Risk of
nocardial infections with anti-tumor necrosis factor therapy.
It later grew nocardial infection, but the specific species was unidentified because our hospital's laboratory could not make that determination.
In the present case, the nocardial infection originated on the skin and then spread hematogenously to the lungs and brain, with the lungs being the primary site of this type of infection in more than 66% of cases.
Nocardial infections most commonly cause pulmonary disease, but can also lead to abscesses of the brain, liver, lungs and other organs.
In Situ Hybridization for Detection of
Nocardial 16S rRNA: Reactivity within Intracellular Inclusions in Experimentally Infected Cynomolgus Monkeys-and in Lewy Body-containing Human Brain Specimens.
19) Ozturk et al (20) described a case of nocardial brain abscess occurring in a renal transplant recipient on an immunosuppressive drug regimen.
Nocardial brain abscess: review of clinical management.
Case series and reviews of nocardiosis in SLE find that diagnosis is frequently made post mortem due to difficulty in clinically distinguishing
nocardial infection from lupus flair, and the delay in diagnosis due to its slow growing properties in laboratory medium (1,4).
Abnormalities in cell-mediated immunity are a major risk factor for
nocardial infection.
Robert A Ollar is an internationally respected Microbiologist and Molecular Biologist with more than 30 years of experience in researching TB, Mycobacterial and
Nocardial Diseases.
3)
Nocardial infections can be difficult to recognize, which leads to misdiagnosis and, consequently, an underestimation of its incidence.
Thus, individuals with impaired T-cell function are at increased risk for
nocardial infection.
