no-reflow phenomenon


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Related to no-reflow phenomenon: Reperfusion injury

no-reflow phenomenon

 [no re´flo]
when cerebral blood flow is restored following prolonged global cerebral ischemia, there is initial hyperemia followed by a gradual decline in perfusion until there is almost no blood flow.

no-reflow phenomenon

Cardiology The finding that restoration of antegrade flow in an occluded epicardial artery in acute MI may not result in recovery of microvascular tissue perfusion; Pts with NRP have lower
1-month ejection fractions, larger end-diastolic volumes, and more persistent heart failure; Pts at high risk with significant zones of no reflow after thrombolytics might need emergency coronary angiography, and benefit from early and aggressive ACE inhibition to prevent LV remodeling. See Ventricular remodeling.
References in periodicals archive ?
On this basis, no-reflow phenomenon easily occurs when the ischemic region cannot immediately be perfused with sufficient blood after recanalization for blood flow recovery.5
In this study, we combined hs-CRP with ET-1 to detect their dynamic changes before and after PCI and the correlation, aiming to provide a scientific basis for the no-reflow phenomenon after PCI.
Chronic pre-treatment of statins is associated with the reduction of the no-reflow phenomenon in the patients with reperfused acute myocardial infarction.
No-reflow phenomenon and endothelial glycocalyx of microcirculation.
"No-reflow phenomenon and prognosis in patients with acute myocardial infarction." Nature Clinical Practice of Cardiovascular Medicine, 2006; 3:499-506.
(2003) Association between hyperglycemia and the no-reflow phenomenon in patients with acute myocardial infarction.
The purpose of our study was to investigate the effect of serotonin levels on no-reflow phenomenon following a primary PCI in patients with acute ST-elevation myocardial infarction.
There was no significant relationship between the vessel responsible for myocardial infarction and no-reflow phenomenon (p=0.91).
No-reflow phenomenon was angiographically defined as a flow of TIMI 2 or less without the presence of dissection, mechanical obstruction, significant residual stenosis or other plausible causes (5,6).
Treatment of no-reflow phenomenon with intracoronary verapamil after primary stent deployment during myocardial infarction.