no-reflow phenomenon


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Related to no-reflow phenomenon: Reperfusion injury

no-reflow phenomenon

 [no re´flo]
when cerebral blood flow is restored following prolonged global cerebral ischemia, there is initial hyperemia followed by a gradual decline in perfusion until there is almost no blood flow.

no-reflow phenomenon

Cardiology The finding that restoration of antegrade flow in an occluded epicardial artery in acute MI may not result in recovery of microvascular tissue perfusion; Pts with NRP have lower
1-month ejection fractions, larger end-diastolic volumes, and more persistent heart failure; Pts at high risk with significant zones of no reflow after thrombolytics might need emergency coronary angiography, and benefit from early and aggressive ACE inhibition to prevent LV remodeling. See Ventricular remodeling.

no-reflow phenomenon

a failure of reperfusion to occur after adequate fluid therapy for shock due to microvascular injury.
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References in periodicals archive ?
There was no significant relationship between the vessel responsible for myocardial infarction and no-reflow phenomenon (p=0.
There is a relationship between the recovery of left ventricular function after an acute myocardial infarction and no-reflow phenomenon, as well.
However, studies investigating the relationship between no-reflow phenomenon after reperfusion and baseline hs-CRP levels have reported conflicting results.
Lower incidence of no-reflow phenomenon has been reported in patients undergoing direct stenting without prediction (41).
Small number of our patient sample and lack of certain diagnostic approaches such as magnetic resonance imaging and myocardial contrast echocardiography in addition to angiographic examination in establishing no-reflow phenomenon in our patients were the limitations of this present study.
Clinical significance of no-reflow phenomenon observed on angiography after successful treatment of acute myocardial infarction with percutaneous transluminal coronary angioplasty.