no-reflow phenomenon
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Related to no-reflow phenomenon: Reperfusion injury
no-reflow phenomenon
[no re´flo]when cerebral blood flow is restored following prolonged global cerebral ischemia, there is initial hyperemia followed by a gradual decline in perfusion until there is almost no blood flow.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
no-reflow phenomenon
Cardiology The finding that restoration of antegrade flow in an occluded epicardial artery in acute MI may not result in recovery of microvascular tissue perfusion; Pts with NRP have lower1-month ejection fractions, larger end-diastolic volumes, and more persistent heart failure; Pts at high risk with significant zones of no reflow after thrombolytics might need emergency coronary angiography, and benefit from early and aggressive ACE inhibition to prevent LV remodeling. See Ventricular remodeling.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.