no-observable-effect level

no-observable-effect level

A clinical trial term of art for a dose of an experimental drug which does not produce an observable toxic effect.
References in periodicals archive ?
2 milligrams per kilogram per day--produced kidney damage, even though it was fourfold lower than the no-observable-effect level used by the U.
Examination of the kidney revealed a deterioration characteristic of the usual course of SLE, including the appearance of immune complexes of antibodies and target cells, even at the lowest chlordecone dose--a dose that would usually be considered a no-observable-effect level.