nitrosureas

nitrosureas

A range of drugs used in the treatment of cancers. The nitrosureas are ALKYLATING AGENTS. Some nitrosureas are also capable of causing cancer.
References in periodicals archive ?
Table 3: Standard Chemotherapies with Known Nephrotoxicity Risk Carboplatin Cisplatin Cyclophosphamide Gemcitabine Methotrexate Mitomycin Nitrosureas Pemetrexed Streptozocin Vinca alkaloids
1) Alkylating agents include the nitrogen mustards (eg cyclophosphamide), nitrosureas (lomustine), platinum compounds (cisplatin) and a variety of others (eg busulfan, temozolomide).
Examples of nitrosureas are Carmustine, Lomustine and Streptozocin.
The most commonly used chemotherapy drugs have been alkylating agents, such as procarbazine (Matulane), temozolomide (Temodar), and the nitrosureas, carmustine (BCNU) and lomustine (CCNU).