nitroimidazoles

nitroimidazoles

antiprotozoal agents, the most common being metronidazole.
References in periodicals archive ?
10) Alcohol should not be consumed during treatment with nitroimidazoles.
El metronidazol y nitroimidazoles similares (tinidazol y secnidazol) muestran actividad in vitro contra muy diversos parasitos protozoicos y bacterias anaerobias.
Cephalosporins were the most frequently prescribed in 162 (81%) patients followed by nitroimidazoles (97, 48.
El uso de nitazoxanida en medicina veterinaria hasta el momento es un poco incipiente, su mecanismo de accion es inhibir una enzima esencial para el metabolismo energetico de estos organismos, piruvato ferredoxina oxidorreductasa (PFOR) [30], similar mecanismo de los nitroimidazoles [31].
Nitroimidazoles, primarily metronidazole, have been the mainstay of treatment for decades.
Nitroimidazoles (such as secnidazole, metronidazole) and their derivatives have been extensively used as antimicrobial drugs [8-10] and has been accepted as drug of choice for anti-infectious therapy to kill microbials in host tissues and organs [11].
In 2008, researchers belonging to NIAID found that Nitroimidazoles kills mtb bacteria by releasing nitric oxide, which is highly poisonous to bacteria.
However, anaerobes are now developing resistance to this Nitroimidazoles also.
The various classes of antibacterial drug included in this report are beta-lactams, macrolides, aminoglycosides, phenicols, quinolones, folate antagonists, tetracyclines, and other miscellaneous agents, which include glycopeptides, nitroimidazoles, lincosamides, lipopeptides, nicotinic acid derivatives, and polypeptide antibiotics.
FDEs are not uncommon and are seen with a host of drugs, including nitroimidazoles (2,3) fluoroquinolones (4,5) and cross sensitivity and poly-sensitivity among different members of the same pharmacological class do exist.
Since the introduction of metronidazole in 1959, nitroimidazoles have been the main treatment for giardiasis.