nitrofurantoin


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nitrofurantoin

 [ni″tro-fu-ran´to-in]
a broad-spectrum antibacterial agent used in treatment of urinary tract infections.

ni·tro·fu·ran·to·in

(nī'trō-fyū-ran'tō-in),
A urinary antibacterial agent with a wide range of activity against both gram-positive and gram-negative organisms; also available as nitrofurantoin sodium for injection.

nitrofurantoin

/ni·tro·fu·ran·to·in/ (-fu-ran´to-in) an antibacterial effective against many gram-negative and gram-positive organisms; used in urinary tract infections.

nitrofurantoin

(nī′trō-fyo͝o-răn′tō-ĭn)
n.
A derivative of nitrofuran, C8H6N4O5, used to treat bacterial infections of the urinary tract.

nitrofurantoin

[nī′trōfyoo͡ran′tō·in, -fyo̅o̅′rəntō′in]
a urinary antibacterial.
indications It is prescribed in the treatment of urinary tract infections caused by some gram-negative bacteria and a few gram-positive bacteria. Some of the more common bacteria that cause urinary tract infections are resistant to it.
contraindications Kidney dysfunction or known hypersensitivity to this drug prohibits its use. It is not given to children under 1 month of age or to pregnant or lactating women. It should be used with caution in people with glucose-6-phosphate dehydrogenase deficiency, vitamin B deficiency, anemia, diabetes mellitus, or electrolyte disturbances.
adverse effects Among the most serious adverse effects is hypersensitivity pneumonitis, which can lead to fibrosis, neurotoxicity, and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency. GI disturbances and fever are common.

ni·tro·fu·ran·to·in

(nī'trō-fyūr-an'tō-in)
A nitrofuran compound (O-[5-nitrofurfurylideneamino]hydantoin) with antimicrobial activity against a wide spectrum of gram-positive and gram-negative bacteria.

nitrofurantoin

A drug that damages bacterial DNA and is used to treat urinary tract infections. The drug is on the WHO official list. Brand names are Furadantin, Macrobid and Macrodantin.

ni·tro·fu·ran·to·in

(nī'trō-fyūr-an'tō-in)
Urinary antibacterial agent with a wide range of activity against both gram-positive and gram-negative organisms.

nitrofurantoin

a nitrofuran derivative antibacterial agent used in the treatment of urinary tract infections.
References in periodicals archive ?
According to 2011 guidelines from the Infectious Diseases Society of America, nonpregnant women with uncomplicated UTIs should be treated with nitrofurantoin or trimethoprimsulfamethoxazole.
717 that nitrofurantoin was still thought to be appropriate when no other suitable alternative antibiotics were available (Obstet Gynecol.
Norfloxacin (75%), Amikacin (75%) > Cloxacillin (25%), Cotrimoxazole (25%), Cefuroxime (25%) and all were susceptible to Nitrofurantoin and Gentamicin.
Because of lower resistance, fosfomycin and nitrofurantoin must be considered as the first choice for the treatment of lower UTIs.
Dr Otiv also admitted on August 30, after her death, preparing a report for the coroner that failed to state that he had prescribed nitrofurantoin to Mrs Gibson and to editing her medical record.
7-9 Because of the indiscriminate use of antibiotics enterococci have acquired resistance against several classes of antimicrobial agents including chloramphenicol tetracyclines glycopeptides quinolones and nitrofurantoin.
Women who take TMP/SMX develop drug concentrations in breast milk that are below recommended maximum safe levels for infants who don't have glucose-6-phosphate dehydrogenase (G6PD) deficiency (SOR: B, a small observational study and expert opinion); treatment with nitrofurantoin and ciprofloxacin also produces low levels in breast milk (SOR: C, extrapolations from small observational studies and expert opinion).
8] We also used the BSAC breakpoints to determine susceptibility of P-haemolytic streptococci to nitrofurantoin.
Staphylococcus aureus, the commonest isolate showed good sensitivity to gentamicin and nitrofurantoin with 75% and 77.
Prasco is pleased to work with Shionogi to extend another of its brands, Furadantin oral suspension, into our authorized generic product line as nitrofurantoin oral suspension," says Prasco CEO E.