nitrofurantoin


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nitrofurantoin

 [ni″tro-fu-ran´to-in]
a broad-spectrum antibacterial agent used in treatment of urinary tract infections.

ni·tro·fu·ran·to·in

(nī'trō-fyū-ran'tō-in),
A urinary antibacterial agent with a wide range of activity against both gram-positive and gram-negative organisms; also available as nitrofurantoin sodium for injection.

nitrofurantoin

/ni·tro·fu·ran·to·in/ (-fu-ran´to-in) an antibacterial effective against many gram-negative and gram-positive organisms; used in urinary tract infections.

nitrofurantoin

(nī′trō-fyo͝o-răn′tō-ĭn)
n.
A derivative of nitrofuran, C8H6N4O5, used to treat bacterial infections of the urinary tract.

nitrofurantoin

[nī′trōfyoo͡ran′tō·in, -fyo̅o̅′rəntō′in]
a urinary antibacterial.
indications It is prescribed in the treatment of urinary tract infections caused by some gram-negative bacteria and a few gram-positive bacteria. Some of the more common bacteria that cause urinary tract infections are resistant to it.
contraindications Kidney dysfunction or known hypersensitivity to this drug prohibits its use. It is not given to children under 1 month of age or to pregnant or lactating women. It should be used with caution in people with glucose-6-phosphate dehydrogenase deficiency, vitamin B deficiency, anemia, diabetes mellitus, or electrolyte disturbances.
adverse effects Among the most serious adverse effects is hypersensitivity pneumonitis, which can lead to fibrosis, neurotoxicity, and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency. GI disturbances and fever are common.

ni·tro·fu·ran·to·in

(nī'trō-fyūr-an'tō-in)
A nitrofuran compound (O-[5-nitrofurfurylideneamino]hydantoin) with antimicrobial activity against a wide spectrum of gram-positive and gram-negative bacteria.

nitrofurantoin

A drug that damages bacterial DNA and is used to treat urinary tract infections. The drug is on the WHO official list. Brand names are Furadantin, Macrobid and Macrodantin.

ni·tro·fu·ran·to·in

(nī'trō-fyūr-an'tō-in)
Urinary antibacterial agent with a wide range of activity against both gram-positive and gram-negative organisms.

nitrofurantoin

a nitrofuran derivative antibacterial agent used in the treatment of urinary tract infections.
References in periodicals archive ?
All study isolates were susceptible to amoxicillin-clavulanate, ciprofloxacin, nitrofurantoin, and vancomycin.
Dr Otiv also admitted on August 30, after her death, preparing a report for the coroner that failed to state that he had prescribed nitrofurantoin to Mrs Gibson and to editing her medical record.
The risks of long-term nitrofurantoin prophylaxis in patients with recurrent urinary tract infection: a recent medico-legal case.
Prasco is pleased to work with Shionogi to extend another of its brands, Furadantin Oral Suspension, into our Authorized Generic product line as Nitrofurantoin Oral Suspension," said Prasco Chief Executive Officer E.
The cumulative effect of the antibiotics as obtained in this study is Gentamicin > Norfloxacin > Nitrofurantoin > Ofloxacin > Ampicillin = Cefuroxime = Chloramphenicol = Amoxillin = Tetracycline = Ciprofloxacin.
Nitrofurantoin prophylaxis for bacteriuria and urinary tract infection in children with neurogenic bladder on intermittent catheterization.
3,4) Recently, there has been an alarming increase in the occurrence of resistance to the drugs commonly prescribed, namely sulfamethoxazole/trimethoprim (SXT/TMP), ciprofloxacin, and nitrofurantoin.
Susceptibility to antimicrobial agents was tested by means of the disk diffusion method according to the National Committee for Clinical Laboratory Standards (NCCLS) guidelines (NCCLS, 2000) for the following antimicrobials: amoxicillin/clavulanic acid (AMC, 30 [micro]g), ampicillin (AMP, 10 [micro]g), apramycin (APR, 15 [micro]g), cephalothin (CEF, 30 [micro]g), chloramphenicol (CHL, 30 [micro]g), enrofloxacin (ENR, 5 [micro]g), gentamicin (GEN, 10 [micro]g), kanamycin (KAN, 20 [micro]g), nitrofurantoin (NIT, 300 [micro]g), streptomycin (STR, 10 [micro]g), tetracycline (TET, 30 [micro]g), and trimethoprim/sulfamethoxazole (SXT, 25 [micro]g), all supplied by Oxoid.
Antibiotic disks (BBL) containing chloramphenicol, ciprofloxacin, gentamicin, kanamycin, lincomycin, nitrofurantoin, moxalactam, polymyxin B, rifampin, streptomycin, sulfa/trimethoprim, and tetracycline were added to the sugar supplemented plates.
Cholestasis: macrolides, phenothiazines, hypoglycemics, imipramine, nitrofurantoin
The drugs most often used to treat routine, uncomplicated UTIs are trimethoprim (Trimpex), trimethoprim/ sulfamethoxazole (Bactrim, Septra, Cotrim), amoxicillin (Amoxil, Trimox, Wymox), nitrofurantoin (Macrodantin, Furadantin), and ampicillin.