nisoldipine


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nisoldipine

 [ni-sol´dĭ-pēn]
a calcium channel blocking agent used in the treatment of hypertension; administered orally.

nisoldipine

/ni·sol·di·pine/ (ni-sol´dĭ-pēn) a calcium channel blocker used in the treatment of hypertension.

nisoldipine

a calcium channel blocker.
indications It causes vasodilation and is prescribed, either alone or in combinations, for the management of hypertension.
contraindications Factors that prohibit its use include hypersensitivity to nisoldipine or other dihydropyridine calcium channel blockers. High-fat meals and grapefruit juice should be avoided because these foods can cause sudden increases in the blood levels of the drug.
adverse effects Fluid retention, headache, nausea, dizziness, pharyngitis, shortness of breath, cough, and palpitations are among the more common adverse effects.

nisoldipine

A CALCIUM CHANNEL BLOCKER drug used to treat angina pectoris and high blood pressure (HYPERTENSION). A brand name is Syscor MR.
References in periodicals archive ?
CA nisoldipine, nimodipine, nitrendipine, nifedipine, and nicardipine have AOA that correlates with their lipophilicity (modified Buege and Aust's method of TBA determination, applied in model of rat brain cortex ischemia/reperfusion) [87].
Drug Interactions: Co-administration of cisapride, pimozide, quinidine, dofetilide, levacetylmethadol (levomethadyl), felodipine, oral midazolam, nisoldipine, triazolam, lovastatin, simvastatin, ergot alkaloids such as dihydroergotamine, ergometrine (ergonovine), ergotamine and methylergometrine (methylergonovine) or methadone with ONMEL[TM] is contraindicated.
Relationship between time after intake of grapefruit juice and the effect on the pharmacokinetics and pharmacodynamics of nisoldipine in healthy subjects.
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The ABCD trial showed higher incidence of myocardial infarction in the nisoldipine arm compared with the ACE inhibitor22.
The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with noninsulin-dependent diabetes and hypertension.
Blood pressure medications known as calcium channel blockers, including felodipine (Plendil), nifedipine (Adalat, Procardia), nimodipine (Nimotop) and nisoldipine (Sular)
Mylan said it's shipping its Nisoldipine ER, the first generic version of Sular in the U.
Relationship between time after intake of grapefruit juice and the effect of pharmacokinetics and pharmacodynamics on nisoldipine in healthy subjects.
The following drugs have been found to interact with grapefruit juice (to be sure of your medications, ask your pharmacist): calcium channel blockers (for high blood pressure)--felodipine (Plendil), nifedipine (Procardia, Adalat), nisoldipine (Sular); immunosuppressant drugs (for organ transplants)--cyclosporine (Neoral, Sandimmune, SangCya), tacrolimus (Prograf); drugs for anxiety, insomnia or depression--diazepam (Valium), triazolam (Halcion), zaleplon (Sonata), carbamazepine (Tegretol), clomipramine (Anafranil).
The extended-release formulation of calcium channel blocker nisoldipine may be particularly effective for hypertensive African Americans, who tend to have high blood pressure levels throughout the night.