nicotinamide mononucleotide


Also found in: Acronyms.

nic·o·tin·a·mide mon·o·nu·cle·o·tide (NMN),

(nik'ā-tin'ă-mīd mon'ō-nū'klē-ō-tīd),
A condensation product of nicotinamide and ribose 5-phosphate, linking the N of nicotinamide to the (β) C-1 of the ribose; in NAD+, the ring is linked by the 5'-phosphoryl residue of the ribose moiety to the 5'-phosphoryl residue of AMP; a precursor in the synthesis of NAD+.

nic·o·tin·a·mide mon·o·nu·cle·o·tide

(NMN) (nik'ō-tin'ă-mīd mon'ō-nū'klē-ō-tīd)
A condensation product of nicotinamide and ribose 5-phosphate, a precursor in the synthesis of NAD+.
References in periodicals archive ?
Morris, "Head to head comparison of short-term treatment with the Nad+ precursor nicotinamide mononucleotide (NMN) and 6 weeks of exercise in obese female mice," Frontiers in Pharmacology, vol.
Imai, "Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice," Cell Metabolism, vol.
Miao, "Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide," Cardiovascular Research, vol.
Chiarugi, "Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo," Biochemical Pharmacology, vol.
A 2017 review of the literature has found that supplementation with NAD+ precursors nicotinamide riboside or nicotinamide mononucleotide increases lifespan in mice.
Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.
THE DISCOVERY: NICOTINAMIDE MONONUCLEOTIDE, A POTENTIAL TREATMENT FOR ADULT-ONSET DIABETES

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