nicotinamide adenine dinucleotide


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Related to nicotinamide adenine dinucleotide: nicotinamide adenine dinucleotide phosphate, adenosine triphosphate

nic·o·tin·a·mide ad·e·nine di·nu·cle·o·tide (NAD, NAD+, NADH),

(nik'ō-tin'ă-mīd ad'ĕ-nīn dī-nū'klē-ō-tīd),
Ribosylnicotinamide 5'-phosphate (NMN) and adenosine 5'-phosphate (AMP) linked by phosphoanhydride linkage between the two phosphoric groups; binds as a coenzyme to proteins, serves in respiratory metabolism (hydrogen acceptor and donor) through alternate oxidation and reduction (NAD+ ⇋ NADH). See also entries under NAD+ and NADP+

nicotinamide adenine dinucleotide

(nĭk′ə-tĭn′ə-mīd′, -tē′nə-)
n.
NAD.

nic·o·tin·a·mide ad·e·nine di·nu·cle·o·tide

(NAD) (nik'ō-tin'ă-mīd ad'ĕ-nēn dī-nū'klē-ō-tīd)
Ribosylnicotinamide 5'-phosphate (NMN) and adenosine 5'-phosphate (AMP) linked by the two phosphoric groups; binds as a coenzyme to proteins, serves in respiratory metabolism (hydrogen acceptor and donor).
See also: entries under NAD and NADP
Synonym(s): diphosphopyridine nucleotide.
References in periodicals archive ?
Caption: Figure 1: Changes in protein expression after spinal cord ischemia reperfusion (I/R) injury and treatment with different dose of nicotinamide adenine dinucleotide ([NAD.sup.+]) (n = 6 per group).
In their study scientists boosted concentrations of a vital compound called NAD (nicotinamide adenine dinucleotide) in the mice's nervous system by giving them NAD's chemical precursor, nicotinamide, a form of vitamin [B.sub.3].
(1) G6PD catalyzes the first oxidation reaction in the pentose phosphate shunt, in which glucose-6-phosphate is dehydrogenated to 6-phosphogluconolactone with the concurrent reduction of nicotinamide adenine dinucleotide phosphate (NADP).
(14) The severe stress induced by the famine probably decreased the efficiency of converting tryptophan into Nicotinamide Adenine Dinucleotide (NAD).
In this role the cycle oxidizes acetate to carbon dioxide and water while yielding reduced NADH (nicotinamide adenine dinucleotide) and FAD[H.sub.2] (flavin adenine dinucleotide) for bioenergetic purposes (Fig.
The activities of pyrimidine nucleotidase (P5'N) and nicotinamide adenine dinucleotide synthase (NADS) are also modified in blood after Pb exposure.
Niadyne, Inc., Tucson, AZ, has a continuous skin cell delivery system whose key ingredient is a patented pro-nicotinamide adenine dinucleotide which enables niacin to be efficiently converted within skin cells to its active form, nicotinamide adenine dinucleotide (NAD), which helps build skin resilience in three different ways.
The measurement is based on the fact that the enzymatic reduction of diacetyl requires the cofactor nicotinamide adenine dinucleotide phosphate (NADPH).
Abbreviations: cyt c, cytochrome c; GA, gibberellic acid; NADH, nicotinamide adenine dinucleotide; PGR, plant growth regulator.
Two of five randomized, controlled trials involving immunologic therapy showed a benefit, as did a randomized, controlled trial of drug therapy (oral reduced nicotinamide adenine dinucleotide).
Two of five randomized, controlled trials involving immunologic therapy showed an overall beneficial effect, as did one randomized, controlled trial using drug therapy (oral reduced nicotinamide adenine dinucleotide).

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