niclosamide


Also found in: Dictionary, Wikipedia.
Related to niclosamide: Levamisole, praziquantel

niclosamide

 [nĭ-klo´sah-mīd]
one of the most effective anthelmintic agents for use against tapeworm infections, including most species that infect humans; it acts by inhibiting anaerobic metabolism.

niclosamide

Parasitology A salicylanilide that kills snails that harbor Schistosoma; internally it is an effective anthelmintic See Schistosomiasis.

niclosamide

A drug used to remove tapeworms. Unlike earlier treatments, it is free from major side effects. The drug is on the WHO official list. A brand name is Yomesan.
References in periodicals archive ?
Other compounds activated only the p53 pathway--including niclosamide, rafoxanide, and chlorfenapyr--or the Nrf2/ARE pathway--including pinacyanol, 1,8-dihydroxy-4, 5-dinitroanthraquinone, 2-aminoanthraquinone, 2-hydrazino-4-(4-aminophenyl) thiazole, 2-hydrazino-4-(4-nitrophenyl)thiazole, and 2-hydrazino-4-phenylthiazole (Table 2).
"We will now take our findings to the next level by evaluating the ability of Niclosamide to treat Parkinson's disease in disease models.
saginata, the number of illnesses may be underestimated because the decrease might also be explained by a shift of treatment from niclosamide to praziquantel for this infection over the past decade in France.
Synthetic pesticides like metaldehyde (2,4,6,8-tetramethyl-1,3,5,7-tetraoxacyclooctane) and niclosamide (2,5-dichloro-4-nitrosalicyanilide) are commonly used molluscicides targeting the GAS.
Wu, "Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1," Xenobiotica, vol.
Bidinosti et al., "Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling," Journal of Biological Chemistry, vol.
The population control of transmitter mollusks is done with niclosamide, a molluscicide recommended by the World Health Organization for control programs [1-3].
Lai, "Drug screening identifies niclosamide as an inhibitor of breast cancer stem-like cells," PLoS ONE, vol.
Additionally, a drug that has been used to treat helminth infections, niclosamide, inhibited viral growth.
Environmental impact of two molluscicides: niclosamide and metaldehyde in a rice paddy ecosystem.