nick


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nick

(nik),
In molecular biology, hydrolytic cleavage of a phosphodiester bond in one strand of a double-stranded polynucleic acid. Compare: cut.

nick

Etymology: ME, nyke, notch
a split in a single strand of DNA that can be made with the enzyme deoxyribonuclease or with ethidium bromide. See also cut.

nick

Molecular biology
noun A single-strand break in a double-stranded nucleic acid, usually DNA, at which point either one or more nucleotides are absent or there is a break in the phosphodiester bond between two adjacent nucleotides on one strand of the nucleic acid (DNA) duplex. Nicked sites are characterised by increased mobility.

verb To effect a nick in a double-stranded nucleic acid (usually DNA).

nick

a single-stranded cut or break in a DNA molecule. Nicking of DNA may form part of a DNA repair mechanism, as occurs after damage caused by, for example, ultraviolet light.

nick

1. said of a mating that is likely to produce superior offspring.
2. slang for body condition; an animal in good body condition is said to be in good nick.
3. a break in a strand of nucleic acid.
References in periodicals archive ?
But instead of getting scared, Nick hits back with a threat of his own.
After breakfast, and after Nick has gathered his fly rod, fly line, and leader box, Hemingway describes Nick's thoughts as he heads to the river: "Nick felt awkward and professionally happy with all his equipment hanging from him" (IOT 147).
Nick was in the same climbing party as American Google executive Dan Fredinburg, who died in the tragedy.
There are so many things about Nick Joaquin that we don't really know about.
Having worn a uniform his entire adult life, and being too young to fully retire, Nick secured a position with the Ottawa Division of the Canadian Corps of Commissionaires.
Charges filed against Nick, 29, of Ashington, Northumberland, were quashed and Nick was freed from prison.
At last, hard-pressed and bleeding, Nick saw the opening he had been waiting for.
We're delighted to do this - Nick is a famous son of Bedworth.
Nick has not yet been consumed by his addiction, but his mother's are on full display.
The deer mount Nick was carrying would end up taking second place in Iowa's nontypical muzzleloader category that weekend, but the story behind the deer is more important to him than the trophy that now adorns his home in western Iowa, where Nick and his family have lived since moving from Kansas City 15 years earlier.
We had Nick evaluated by an experienced team of professionals, and the results were always grim.