Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol 2002;3(12): 919-931.
Translated protein from SNX10 gene has 201 amino acids and belongs to Sorting Nexin (SNX) family that are cytoplasmic and membrane-associated proteins playing various roles in endocytosis and protein trafficking (4).
Tektins are microtubule-associated cytoskeletal proteins essential for generating complex, long-range patterns of binding sites for axonemal components, such as nexins
, radial spokes, and dynein arms (Norrander et al.
We used the following: Apoptosis detection by the terminal deoxynucleotidyl transferase--mediated dUTP nick-end labeling (TUNEL) method (Roche, Mannheim, Germany), apoptosis detection by the annexin V method (Nexins
Research, Kattendijke, The Netherlands), enzyme-linked immunosorbent assay (ELISA) for tumor necrosis factor [alpha] (TNF[alpha]) and IL-6 (R&D Systems, Minneapolis, MN, USA) and for prostaglandin [E.sub.2] (PG[E.sub.2]; Endogen, Woburn, MA, USA).
Wang et al., "MicroRNA-95 promotes cell proliferation and targets sorting nexin
1 in human colorectal carcinoma," Cancer Research, vol.
16 (SNX16) encodes a member of the sorting nexin
family, which contain a phox (PX) domain.
Gating con nexin
43 channels reconstituted in lipid vesicles by mitogen-activated protein kinase phosphorylation.