For baseline comparison, a nevus with corresponding p16 immunohistochemistry characteristically shows strong and diffuse staining pattern of nevocytes
(Figure 1, b).
They are classified into jonctional nevi (the growth of nevocytes
on the inferior layers of epidermis and at the dermal-epidermal junction), intradermal nevi (dermic nevus growth) and compound nevi (nevus nests localized at the dermal-epidermal jonction and at the dermal area).
In the halo pattern, many lymphocytes are associated with the nevocytes
. Spindling or fusiform cells resembling Schwann cells create a fascicular pattern.