nevirapine


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nevirapine

 [nĕ-vir´ah-pēn]
a nonnucleoside human immunodeficiency virus-1 (HIV-1) reverse transcriptase inhibitor that acts by interfering with the ability of the virus to replicate; used in combination with other antiretroviral agents in treatment of HIV-1 infection, administered orally.

nevirapine

/ne·vir·a·pine/ (nĕ-vir´ah-pēn) a nonnucleoside inhibitor of HIV-1reverse transcriptase, used in combination with other antiretroviral agents in the treatment of HIV infection.

nevirapine

(nə-vîr′ə-pēn′, -pĭn)
n.
An antiviral drug, C15H14N4O, that is a non-nucleoside reverse transcriptase inhibitor and is used in combination with other drugs for the treatment of HIV infection.

nevirapine

an antiretroviral nonnucleoside reverse transcriptase inhibitor.
indication It is prescribed in combination for the treatment of human immunodeficiency virus infection.
contraindications It should not be given to patients with an allergy or sensitivity to the medication or to patients taking ketoconazole or oral contraceptives. When used alone, there is rapid and uniform appearance of viral resistance.
adverse effects The side effects most often reported include headache, rash, drug fever, and diarrhea.

nevirapine

Viramune® AIDS An antiretroviral non-nucleoside reverse transcriptase inhibitor, combined with nucleoside RTIs to manage HIV infection Adverse effects Rash. See Nonnucleoside reverse transcriptase inhibitor, TIBO. Cf Antiretroviral agent, Delavirdine.

nevirapine

A non-nucleoside reverse transcription inhibitor drug used in combination with other antiretroviral drugs to treat HIV infections. The drug is on the WHO official list. A brand name is Viramune.
References in periodicals archive ?
13] In this study, zidovudine + lamivudine + nevirapine based combination was prescribed in majority of the patients and zidovudine being a myelosuppressive drug is known to cause anemia within 3 months of initiating therapy.
Nevirapine Extended-release Tablets, 100 mg, had US sales of approximately USD67,000 for the 12 months ending 30 Sept 2015, according to IMS Health.
During the delivery of seropositive pregnant woman, a single dose regime of nevirapine 200 mg tablet is given at the time of onset of labour and nevirapine syrup 2mg/kg of body weight is offered to the babies within 72 hrs of birth.
On day 3 after admission, he was prescribed 300 mg zidovudine twice daily, 150 mg lamivudine twice daily and 200 mg nevirapine daily.
Policy makers can now make informed decisions regarding the WHO 2010 prevention of mother-to-child transmission (PMTCT) guidelines and the combined use of nevirapine and co-trimoxazole prophylaxis for extended periods of time.
The clinics followed NACO guidelines for PPTCT and administered a single dose of nevirapine to the mother at the time of delivery and one dose to the infant within 72 h after birth.
10) The new guidelines provide HAART to all pregnant women with CD4 cell counts [less than or equal to] 350 cells/[micro]l, dual prophylaxis from 14 weeks of pregnancy, nevirapine and tenofovir/emtricitabine as tail cover, and either 6 weeks' nevirapine prophylaxis to infants of mothers on HAART or to non-breastfeeding HIV-exposed infants or continued nevirapine prophylaxis for breastfeeding HIV-exposed infants until 1 week after breastfeeding stops.
In this effort, the investigators hoped to determine if the antiretroviral drug nevirapine, manufactured by Boehringer, administered to HIV-positive mothers and their babies after birth could prevent transmission of the virus.
VERxVE is a pivotal trial that compared the frequently prescribed lipid-friendly* antiretroviral ViramuneEeA IR with once daily nevirapine (ViramuneEeA XR.
Interestingly, hepatotoxicity to either efavirenz or nevirapine appears not to increase the risk on exposure to the alternative NNRTI [38,39].
These enzyme-inducing ARV drugs include non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as nevirapine and protease inhibitors such as ritonavir.
Nevirapine is an important antiretroviral agent in the prevention of mother-to-child transmission of HIV.