Chronic neutrophilic leukemia (CNL) is a rare and fatal myeloproliferative disease, first described by Tuohy in 1920.
An association between chronic neutrophilic leukemia and multiple myeloma with a study of cobalamin-binding proteins.
Cytobiologic and clinical aspects in a patient with chronic neutrophilic leukemia after thorotrast exposure.
Chronic neutrophilic leukemia associated with polycythemia vera.
Cervantes F, Rozman M, Vives-Corrons J-L, et al: Chronic neutrophilic leukemia with dysplastic features.
Chronic neutrophilic leukemia and myeloma: Report on long survival.
Chronic neutrophilic leukemia preceding for seven years the development of multiple myeloma.
As for the less common MPNs, mutations in the receptor for colony-stimulating factor 3 (CSF3R), initially identified in patients with severe congenital neutropenia, (68-70) have been described in 59% of patients with chronic neutrophilic leukemia
or atypical chronic myelogenous leukemia.