Theilgaard-Monch, "Neutrophil granules
: a library of innate immunity proteins," Trends in Immunology, vol.
Our scan of the literature revealed no studies investigating the conversion into chemerin of inactive prochemerin and substances released from activated neutrophil granules
and the diagnostic significance of serum levels thereof in TT.
There are four main types of neutrophil granules
. Azurophilic (primary) granules contain MPO, defensins, and proteinases.
Suggested mechanisms of action of PTU-induced, [ANCA.sup.+] vasculitis include conversion of PTU into cytotoxic products by the release of myeloperoxidase from neutrophil granules
, (13) activation of B cells by immunogenic T cells in the presence of myeloperoxidase, (14) and interaction of PTU with myeloperoxidase that changes the heme structure of enzymes, which then act as hapten.
: a library of innate immunity proteins.
He then treated the cultured cells with human neutrophil peptide-1, one of the three defensins found in large concentrations in neutrophil granules
Larsson et al., "Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules
and associates with the cell surface after stimulation with fMLP" Journal of Leukocyte Biology, vol.