Pseudobacteraemia in a patient with neutropenic fever
caused by a novel paenibacillus species: Paenibacillus hongkongensis sp.
On day 16, she was readmitted with neutropenic fever
and herpes labialis infection.
An initial round of chemotherapy was given, but he developed neutropenic fever
and ARDS and after a few days life support treatment was withdrawn.
The most common grade 3 and 4 adverse events that occurred were neutropenia (32 percent), neutropenic fever
(11 percent) and anemia (11 percent).
Darinaparsin was very well tolerated with neutropenic fever
as a severe adverse event in 1 patient.
In addition, the availability of newer broad spectrum antifungal agents with a good safety profile raise the possibility of using mold-active prophylaxis in patients at high risk for invasive fungal infections without the need to empirically modify antifungal therapy solely on persistent neutropenic fever
of unknown etiology.
The most common adverse events were fever (85%), chills (73%), nausea (70%), vomiting (63%), asthenia (44%), diarrhea (38%), abdominal pain (37%), headache (35%), stomatitis (32%), dyspnea (32%), epistaxis (31%), hypokalemia (31%), anorexia (29%), sepsis (25%), constipation (25%), local reaction (25%), nonspecific rash (22%), herpes simplex (22%), and neutropenic fever