neutralization

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neu·tral·i·za·tion

(nū'trăl-i-zā'shŭn),
1. The change in reaction of a solution from acid or alkaline to neutral by the addition of just a sufficient amount of an alkaline or of an acid substance, respectively.
2. The rendering ineffective of any action, process, or potential.

neutralization

[-īzā′shən]
Etymology: L, neutralis + Gk, izein, to cause
the interaction between an acid and a base that produces a solution that is neither acidic nor basic. The usual products of neutralization are a salt and water. neutralize, v.

neu·tral·i·za·tion

(nū'trăl-ī-zā'shŭn)
1. The change in reaction of a solution from acid or alkaline to neutral by the addition of just a sufficient amount of an alkaline or an acid substance, respectively.
2. The rendering ineffective of any action, process, or potential.
Synonym(s): neutralisation.

neutralization

1. A technique for determining the power of an ophthalmic lens. It is accomplished by placing a lens of known power and opposite sign in contact with the unknown lens and moved back and forth in a plane perpendicular to the line of sight until the observation of movement (against or with) of the distant image seen through the lenses disappear. The unknown lens will have the opposite power to that which neutralizes this apparent movement. 2. A method of breaking down hydrogen peroxide from a contact lens (mostly soft) following contact lens disinfection to avoid possible irritation to ocular tissues. This can be achieved by rinsing and dilution with saline, by using a solution with an enzyme catalase or a platinum disc incorporated into the lens case, or with a chemical agent such as sodium pyruvate or sodium thiosulfate. See disinfection; focimeter.

neu·tral·i·za·tion

(nū'trăl-ī-zā'shŭn)
1. The change in reaction of a solution from acid or alkaline to neutral by the addition of a sufficient amount of an alkaline or an acid substance, respectively.
2. The rendering ineffective of any action, process, or potential.
Synonym(s): neutralisation.

neutralization,

n the reaction of an acid with a base.

neutralization

the state of having been converted to neutrality from acid or base. Used also in microbiology to indicate neutralization of a toxin or of infectivity.

neutralization tests
tests based on the ability of an antibody to neutralize the biological activity of an antigen. These may utilize antitoxins and toxins or immune serum and viruses or bacteria. The tests are often quantitative whereby antibody (serum) is serially diluted; the reciprocal of the highest dilution of serum neutralizing a standard amount of toxin or virus or bacteria is the neutralizing antibody titer of that serum.
References in periodicals archive ?
000 RFU as saturation signal; VNT, virus neutralization test (highest neutralizing serum dilution indicated); NT, not tested; --, negative.
double dagger]) MERS-CoV 1 -- 2 -- 3 -- 4 640 5 >5,120 6 2,560 7 >5,120 8 >5,120 9 >5,120 10 >5,120 11 >5,120 Serum Neutralization test no.
Arbovirus neutralization tests with Peruvian sera in Vero cell cultures.
Serologic assays have been used to detect DOBV infection in patients in Turkey, but focus reduction neutralization tests have not been used for serotyping.
ELISA+ ELISA+t Megachiroptera Cynopterus sphinx 2/2 0/3 Rousettus leschenaulti 18/20 2J/31 Total 20/22 2/34 Microchiroptera Chaerephon plicata Hipposideros armiger Hipposideros cineraceus Hipposideros larvatus Hipposideros pomona Hypsugo cadornae Megaderma spasma Miniopterus magnater Scotophilus kuhi Unidentified Total * +, positive; WB, Western blot; NT, neutralization test.
These conclusions were supported by virus neutralization test results.
Screening of pig sera for antibodies to Japanese encephalitis virus using a dot enzyme immunoassay and IgM capture ELISA: comparison with the hemagglutination inhibition and plaque reduction neutralization tests.
Thirty-nine samples (2 samples had insufficient amounts of plasma remaining) were analyzed by using NiV and HeV serum neutralization tests (SNTs) under Biosafety Level 4 conditions (10).
To investigate the presence of Lagos bat virus (LBV)-specific antibodies in megachiroptera from West Africa, we conducted fluorescent antibody virus neutralization tests.
36 * Analysis used an 80% neutralization cutoff in plaque-reduction neutralization tests (PRNTs).