neurotrophic factor


Also found in: Acronyms.

neurotrophic factor

 A generic term for any of a family of substances with roles in maintenance and survival of neurons–eg, secretory proteins, nerve growth factors–see there, brain-derived growth factor, neurotrophin-3.
References in periodicals archive ?
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats," Molecular Neurobiology, 2018
The real-time-quantitative polymerase chain reaction was measured with the Synergy Brands method, including the genes such as nerve growth factor (NGF), glial cell line-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), neurotrophic factor 3 (NTF3), neurotrophic factor 4/5 (NTF4/5), and glyceraldehydes phosphate dehydrogenase (GAPDH), the related primers are shown in [Table 1].
These compounds elicit mild increases in energy expenditure that result in strengthening cellular survival similar to the positive effects seen with fasting and exercise, and also induce an important neurotrophin, brain derived neurotrophic factor, involved in cognition and neural growth.
9) Retinal glial cells can produce several neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), and nerve growth factor (NGF) that have neuroprotective effects under pathological conditions.
The main mood stabilizers lithium and valproic acid enhance the expression of BDNF while the effects of typical and atypical antipsychotic agents on neurotrophic factor expression remain less well defined.
GDNF is a neurotrophic factor that has been shown in preclinical systems to promote axon growth and protect dopaminergic neurons when delivered directly to the diseased cells for an extended duration.
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration.
The study, which suggested that acupuncture protects brain neurons against injury with heroin relapse by promoting brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression, was published in the Neural Regeneration Research.
Differential expression of brain-derived neurotrophic factor and neurotrophin 3 mRNA in lingual papillae and taste buds indicates roles in gustatory and somatosensory innervation.
Expression of brain-derived neurotrophic factor (BDNF) and inducible nitric oxide synthase (iNOS) in rat astrocyte cultures treated with Levetiracetam.
2010) Brain-derived neurotrophic factor regulates satellite cell differentiation and skeletal muscle regeneration.

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