neurotoxicity


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Related to neurotoxicity: Glutamate neurotoxicity

neurotoxicity

 [noor″o-tok-sis´ĭ-te]
the ability to exert a destructive or poisonous effect upon nerve tissue. adj., adj neurotox´ic.

neurotoxicity

/neu·ro·tox·ic·i·ty/ (noor″o-tok-sis´it-e) the quality of exerting a destructive or poisonous effect upon nerve tissue.neurotox´ic

neurotoxicity

[-toksis′itē]
Etymology: Gk, neuron, nerve, toxikon, poison
the ability of a drug or other agent to destroy or damage nervous tissue.

neurotoxicity

The degree to which a substance, including a therapeutic agent, can damage the nervous system.

neurotoxicity

the quality of exerting a destructive or poisonous effect upon nerve tissue.
References in periodicals archive ?
The paper on neurotoxicity was published online in Cancer Discovery; the one on cytokine release syndrome appeared online in the journal Blood.
Investigations of the current study further strengthen the already documented mechanisms of neurotoxicity.
This suggests that the mechanism of OB neurotoxicity induced by PX and GDX had some differences from the pathogenesis of PD.
Associated hazards include: acute toxicity, liver toxicity, kidney toxicity, reproductive /developmental toxicity, neurotoxicity, immunotoxicity and sensitization.
Tolerance is reversible, while neurotoxicity is not.
11) The reason is that acute psychosis is associated with neuro-inflammation, which leads to neurotoxicity.
Drugs which were used and may potentially lead to neurotoxicity in traumatic patients with advanced CKD are shown in [Table 1].
Ethanol treatment: The zebrafish embryos were obtained as described above and were treated with 250 mM ethanol for 1 h and incubated with fresh fish water until 24 hpf and screened for neurotoxicity and apoptosis.
3] Lithium-related neuropsychiatric symptoms are polymorphous and may be difficult to differentiate from other disorders, so before concluding that lithium is responsible for the observed neurotoxicity, coexistent confounding pathologies including fever, infection, metabolic disturbances, and epilepsy have to be ruled out.
6) The severity of vincristine neurotoxicity increases with higher dosage, patient hypersensitivity to vincristine, pre-existing liver dysfunction, and concomitant use of other metabolism-inhibiting drugs such as allopurinol, erythromycin, isoniazid, phenytoin, or itraconazole.
An EFSA statement released in December said experts had found that the pesticides "may adversely affect the development of neurons and brain structures associated with functions such as learning and memory" in humans and that "some current guidance levels for acceptable exposure may not be protective enough to safeguard against developmental neurotoxicity and should be reduced.
The report describes profitable opportunities for NSC research product development, including cell-based therapies and standardized neurotoxicity assays.