neurotensin


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neurotensin

 [noor″o-ten´sin]
a tridecapeptide that induces vasodilation and hypotension; present in the brain and intestine and postulated to be a neurotransmitter.

neu·ro·ten·sin

(nū'rō-ten'sin), [MIM*162650]
A 13-aminoacyl peptide neurotransmitter found in synapsomes in the hypothalamus, amygdala, basal ganglia, and dorsal gray matter of the spinal cord; plays a role in pain perception but its analgesic effects are not blocked by opioid antagonists; it also affects pituitary hormone release and gastrointestinal function.

neu·ro·ten·sin

(nūr'ō-ten'sin)
A 13-amino acid peptide neurotransmitter found in synapsomes in the hypothalamus, amygdala, basal ganglia, and dorsal gray matter of the spinal cord.

neu·ro·ten·sin

(nū'rō-ten'sin) [MIM*162650]
A 13-amino acid peptide neurotransmitter in synapsomes in the hypothalamus, amygdala, basal ganglia, and dorsal gray matter of the spinal cord.
References in periodicals archive ?
(20.) McCormick SE, Stoessl AJ Central administration of the neurotensin receptor antagonist SR48692 attenuates vacuous chewing movements in a rodent model of tardive dyskinesia.
Scientists at the University of Texas Medical Branch at Galveston (UTMB) have discovered that curcumin, an active ingredient in turmeric, blocks the activity of neurotensin, a gastrointestinal hormone implicated in the development of colorectal cancer.
These unnatural amino acids can be used to replace their natural counterparts in some hormones (eg Neurotensin) to increase their half-life inside a biological system.
(Rahway, NJ) has patented a new family of receptors, growth hormone secretagogue-related receptors, which exhibit moderate sequence identity to both the growth hormone secretagogue receptor (GHS-R) and the neurotensin receptor (NT-R).
The cerebral ganglion of ascidians has been shown to have many neurons immunoreactive for vertebrate neuropeptides such as GnRH, bombesin, and neurotensin (11, 12].
Involvement of spinal monoaminergic pathways in antinociception produced by substance P and neurotensin in rodents.
In a second report, graduate student Yigong Xing and her colleagues describe several experiments in which they tracked RNA made by two genes, one carrying the code for a nerve-cell chemical called neurotensin and the other coding for a structural component of cells called fibronectin.
Analysis of argentinated peptide complexes using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Peptide = oxytocin, arg(8)-vasopressin, bradykinin, bombesin, somatostatin, neurotensin. Rap Commun Mass Spectrom 2016;30:1313-22.
The role of neurotensin (NT), a peptide widely distributed in the central and peripheral nervous systems, which can enhance the ability of CRH to increase skin vascular permeability, has also been studied in patients with psoriasis.
One of these promising candidates in GI cancers such as colorectal cancers (CRC) is the tridecapeptide neurotensin (NTS) [1-3].
Eiden, "Interleukin-1 alpha and tumor necrosis factor-alpha differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin, and substance P biosynthesis in chromaffin cells," Endocrinology, vol.