(20.) McCormick SE, Stoessl AJ Central administration of the neurotensin
receptor antagonist SR48692 attenuates vacuous chewing movements in a rodent model of tardive dyskinesia.
Scientists at the University of Texas Medical Branch at Galveston (UTMB) have discovered that curcumin, an active ingredient in turmeric, blocks the activity of neurotensin
, a gastrointestinal hormone implicated in the development of colorectal cancer.
These unnatural amino acids can be used to replace their natural counterparts in some hormones (eg Neurotensin
) to increase their half-life inside a biological system.
(Rahway, NJ) has patented a new family of receptors, growth hormone secretagogue-related receptors, which exhibit moderate sequence identity to both the growth hormone secretagogue receptor (GHS-R) and the neurotensin
The cerebral ganglion of ascidians has been shown to have many neurons immunoreactive for vertebrate neuropeptides such as GnRH, bombesin, and neurotensin
Involvement of spinal monoaminergic pathways in antinociception produced by substance P and neurotensin
In a second report, graduate student Yigong Xing and her colleagues describe several experiments in which they tracked RNA made by two genes, one carrying the code for a nerve-cell chemical called neurotensin
and the other coding for a structural component of cells called fibronectin.
Analysis of argentinated peptide complexes using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Peptide = oxytocin, arg(8)-vasopressin, bradykinin, bombesin, somatostatin, neurotensin
. Rap Commun Mass Spectrom 2016;30:1313-22.
The role of neurotensin
(NT), a peptide widely distributed in the central and peripheral nervous systems, which can enhance the ability of CRH to increase skin vascular permeability, has also been studied in patients with psoriasis.
One of these promising candidates in GI cancers such as colorectal cancers (CRC) is the tridecapeptide neurotensin
Eiden, "Interleukin-1 alpha and tumor necrosis factor-alpha differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin
, and substance P biosynthesis in chromaffin cells," Endocrinology, vol.