neurotensin

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neurotensin

[noor″o-ten´sin]

a tridecapeptide that induces vasodilation and hypotension; present in the brain and intestine and postulated to be a neurotransmitter.

neu·ro·ten·sin

(nū'rō-ten'sin), [MIM*162650]

A 13-aminoacyl peptide neurotransmitter found in synapsomes in the hypothalamus, amygdala, basal ganglia, and dorsal gray matter of the spinal cord; plays a role in pain perception but its analgesic effects are not blocked by opioid antagonists; it also affects pituitary hormone release and gastrointestinal function.

Farlex Partner Medical Dictionary © Farlex 2012

neu·ro·ten·sin

(nūr'ō-ten'sin)

A 13-amino acid peptide neurotransmitter found in synapsomes in the hypothalamus, amygdala, basal ganglia, and dorsal gray matter of the spinal cord.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

neu·ro·ten·sin

(nū'rō-ten'sin) [MIM*162650]

A 13-amino acid peptide neurotransmitter in synapsomes in the hypothalamus, amygdala, basal ganglia, and dorsal gray matter of the spinal cord.

Medical Dictionary for the Dental Professions © Farlex 2012

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References in periodicals archive ?

(20.) McCormick SE, Stoessl AJ Central administration of the neurotensin receptor antagonist SR48692 attenuates vacuous chewing movements in a rodent model of tardive dyskinesia.

Efectividad de la ivermectina en un modelo de disquinesia tardia inducida por haloperidol en ratas

Scientists at the University of Texas Medical Branch at Galveston (UTMB) have discovered that curcumin, an active ingredient in turmeric, blocks the activity of neurotensin, a gastrointestinal hormone implicated in the development of colorectal cancer.

Ayurvedic Spice Shown to Fight Colon Cancer

These unnatural amino acids can be used to replace their natural counterparts in some hormones (eg Neurotensin) to increase their half-life inside a biological system.

Chemistry and chemical engineering

(Rahway, NJ) has patented a new family of receptors, growth hormone secretagogue-related receptors, which exhibit moderate sequence identity to both the growth hormone secretagogue receptor (GHS-R) and the neurotensin receptor (NT-R).

Merck obtains United States patent

The cerebral ganglion of ascidians has been shown to have many neurons immunoreactive for vertebrate neuropeptides such as GnRH, bombesin, and neurotensin (11, 12].

Light-Sensitive Voltage Responses in the Neurons of the Cerebral Ganglion of Ciona savignyi (Chordata: Ascidiacea)

Involvement of spinal monoaminergic pathways in antinociception produced by substance P and neurotensin in rodents.

Fibromyalgia and its primary care implications

In a second report, graduate student Yigong Xing and her colleagues describe several experiments in which they tracked RNA made by two genes, one carrying the code for a nerve-cell chemical called neurotensin and the other coding for a structural component of cells called fibronectin.

Tracking RNA: scientists finally glimpse the sites of RNA processing

Analysis of argentinated peptide complexes using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Peptide = oxytocin, arg(8)-vasopressin, bradykinin, bombesin, somatostatin, neurotensin. Rap Commun Mass Spectrom 2016;30:1313-22.

Neuropeptides in Obesity and Metabolic Disease

The role of neurotensin (NT), a peptide widely distributed in the central and peripheral nervous systems, which can enhance the ability of CRH to increase skin vascular permeability, has also been studied in patients with psoriasis.

The Pathophysiological Mechanisms and the Quest for Biomarkers in Psoriasis, a Stress-Related Skin Disease

One of these promising candidates in GI cancers such as colorectal cancers (CRC) is the tridecapeptide neurotensin (NTS) [1-3].

A Review of the Role of Neurotensin and Its Receptors in Colorectal Cancer

Eiden, "Interleukin-1 alpha and tumor necrosis factor-alpha differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin, and substance P biosynthesis in chromaffin cells," Endocrinology, vol.