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the central nervous system manifestations of tertiary syphilis, which may be divided into two groups, asymptomatic and symptomatic; see also general paresis and tabes dorsalis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Infection of the central nervous system by Treponema pallidum (syphilis); there are several subdivisions, including asymptomatic neurosyphilis, meningeal neurosyphilis, meningovascular neurosyphilis, paretic neurosyphilis, and tabetic neurosyphilis.
Farlex Partner Medical Dictionary © Farlex 2012
neurosyphilisAny of the rare neurological manifestations of tertiary syphilis.
Lightning-like pain, ataxia, optic nerve degeneration leading to blindness, urinary incontinence, loss of position sense, neuropathic arthropathy (Charcot joints), personality changes, aphasia, paralysis, seizures. Patients with early syphilis who are co-infected with HIV may not respond to high-dose penicillin G, leading to an increase in Tertiary syphilis.
Clinical forms of neurosyphilis
• Asymptomatic with only a positive VDRL in the CSF.
• General paresis or chronic meningoencephalitis.
• Meningovascular or thromboembolic with cerebral infarction or cranial nerve defects.
• Tabes with degeneration of the posterior columns of the spinal cord and nerve roots, decreased peripheral reflexes and proprioceptive sensation, evoking Charcot’s joints.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
neurosyphilisNeurology Any of the rare neural changes of 3º syphilis Clinical Lightning-like pain, ataxia, optic nerve degeneration → blindness, urinary incontinence, loss of position sense, Charcot's joints, personality changes, aphasia, paralysis, seizures. See STS-RPR, VDRL. See Charcot's joints, Windswept cortex, Tabes dorsalis. Cf Quaternary syphilis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
Infection of the central nervous system by Treponema pallidum.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
neurosyphilisAny syphilitic infection of the nervous system. This is usually a late (tertiary) manifestation of untreated SYPHILIS, but may occur in adolescence. Its effects are widespread and include TABES DORSALIS, general paralysis of the insane (general paresis or GPI), dementia and involvement of the blood vessels of the brain and the brain coverings (meningovascular syphilis).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005