Morphology of two electrotonically-coupled giant
neurosecretory neurons in the snail.
chorus, the visceral ganglia are associated with the adductor posterior muscle, having
neurosecretory cells located preferentially in the dorsal area (Fig.
Ugrumov, "Developing hypothalamus in differentiation of
neurosecretory neurons and in establishment of pathways for neurohormone transport," International Review of Cytology, vol.
Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in
neurosecretory cells and cortical neurons.
Molecular cloning of endopin 1, a novel serpin localized to
neurosecretory vesicles of chromaffin cells.
Magnocellular
neurosecretory cells produce the AVP that is found in peripheral blood.
Prostatic NE cells play a role in homeostasis in the prostate by producing a variety of
neurosecretory products having growth-promoting activities, including serotonin, calcitonin, and parathyroid hormone-related peptides [6, 7].
Chromogranin A, by comparison, is part of the
neurosecretory hormone granules; therefore, evidence of its presence is dependent on the number of vesicles present.
Matsuda, "A case of Kabuki make-up syndrome with central diabetes insipidus and growth hormone
neurosecretory dysfunction," Acta paediatrica Japonica; Overseas edition, vol.
However, typical immunohistochemical markers of
neurosecretory tumors including S-100, neuron-specific enolase, chromogranin, and synaptophysin have not been detected [13].
ADH deficiency develops only after extensive destruction of the hypothalamic
neurosecretory cells [11].
This interpretation is, obviously, valid for the cases of GHD deriving from
neurosecretory dysfunction and not organic hypothalamus-pituitary diseases, which can be identified in fibromyalgic patients with GHD [14].
