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Related to neurosarcoma: Neurofibrosarcoma


a sarcoma with neuromatous elements.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


A sarcoma with neuromatous elements; includes neurofibrosarcoma, neurogenic sarcoma, and malignant schwannoma.
Farlex Partner Medical Dictionary © Farlex 2012

malignant peripheral nerve sheath tumour

A poorly understood malignancy, presumably of Schwann cell origin, which is thought to arise from the neural crest. It is the most common malignancy of peripheral nerves, and represents 5 to 10% of all soft-tissue tumours. It occurs in the lower extremities in relatively young patients (age 20 to 50). Half of cases occur in patients with neurofibromatosis type 1, in which the male:female ratio is 4:1; 2/3 of MPNSTs arise from neurofibromas, 1/3 arise de novo. Origin from pre-existing schwannomas, ganglioneuromas or phaeochromocytomas are rare; 10% arise in a background of therapeutic radiation.
Wide local excision; radiation and chemotherapy have been used with varying degrees of failure.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


A malignant tumor arising from the cells of Schwann in the sheaths of nerve fibres. Also known as a malignant schwannoma.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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