neurosarcoma


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Related to neurosarcoma: Neurofibrosarcoma

neurosarcoma

 [noor″o-sahr-ko´mah]
a sarcoma with neuromatous elements.

neu·ro·sar·co·ma

(nū'rō-sar'kō'mă),
A sarcoma with neuromatous elements; includes neurofibrosarcoma, neurogenic sarcoma, and malignant schwannoma.

neurosarcoma

/neu·ro·sar·co·ma/ (noor″o-sahr-ko´mah) a sarcoma with neural elements.

neurosarcoma

[-särkō′mə]
Etymology: Gk, neuron + sarx, flesh, oma, tumor
a malignant neoplasm composed of nerve, connective, and vascular tissues. Also called malignant neuroma.

malignant peripheral nerve sheath tumour

A poorly understood malignancy, presumably of Schwann cell origin, which is thought to arise from the neural crest. It is the most common malignancy of peripheral nerves, and represents 5 to 10% of all soft-tissue tumours. It occurs in the lower extremities in relatively young patients (age 20 to 50). Half of cases occur in patients with neurofibromatosis type 1, in which the male:female ratio is 4:1; 2/3 of MPNSTs arise from neurofibromas, 1/3 arise de novo. Origin from pre-existing schwannomas, ganglioneuromas or phaeochromocytomas are rare; 10% arise in a background of therapeutic radiation.
 
Management
Wide local excision; radiation and chemotherapy have been used with varying degrees of failure.

neurosarcoma

A malignant tumor arising from the cells of Schwann in the sheaths of nerve fibres. Also known as a malignant schwannoma.

neurosarcoma

a sarcoma with neuromatous elements.