The mass and dural thickening characteristic of GW can reach and injure various levels of the spinal cord according to their length and must be differentiated from other diseases such as neurosarcoidosis
, cancer, infectious meningitis, tuberculosis and neurosyphilis through clinical manifestations radiological exams and biopsy of the lesion (6,7).
A study presented at the 2015 EULAR meeting in Rome showed high-dose methotrexate in the 25- to 30-mg/wk range was significantly more effective than mycophenolate mofetil in preventing relapses of neurosarcoidosis
(Ann Rheum Dis.
In October 2015 he was diagnosed with neurosarcoidosis
Dougie Princes and this February he was told that in five to 10 years he would probably only be able to walk with two walking sticks as a best case scenario.
Table 2 Example of a Latin square Idiopathic Diseases pulmonary Primary sclerosing Neurosarcoidosis
Participants fibrosis (IPF) cholangitis (PSC) (NS) P1 Wikipedia Access Medicine Up To Date P2 Access Medicine UpToDate Wikipedia P3 UpToDate Wikipedia Access Medicine
The differential diagnosis of pulmonary and meningeal cryptococcosis includes tuberculosis, a metastatic malignancy of brain, neurosarcoidosis
, and histiocytosis.
Heerfordt- WaldenstrAlm syndrome is a rare manifestation of neurosarcoidosis
and has to be included in the differential diagnosis of facial nerve palsy.
Occasionally a CT or MRI head scan is required when demyelination, lymphoma or neurosarcoidosis
Non-infectious granulomatous lesions including neurosarcoidosis
was excluded with normal S.
1,3) Other similar entities include neurosarcoidosis
, vasculitis, progressive multifocal leukoencephalopathy, gliomatosis cerebri, CNS lymphoma and posterior reversible encephalopathy syndrome.
Other rare causes of white matter hyperintensities include cerebral vasculitis, primary angiitis, leucodystrophies, infective conditions such as Lyme disease and the neurosarcoidosis
presenting as longitudinally extensive transverse myelitis.
2010 cavitary infection azathioprine therapy for neurosarcoidosis
Monju A et al.