neuroprotective agent

neuroprotective agent

Neurology Any agent or drug that protects the brain from secondary injury caused by stroke. See Stroke.
References in periodicals archive ?
In conclusion, ginsenoside Rg1 as a ginsenoside neuroprotective agent could improve neurological injury, attenuate blood brain barrier disruption and downregulate aquaporin 4 expression induced by cerebral ischemia/reperfusion insults in rats.
These results demonstrate that GTPs may act as a potential neuroprotective agent against BBB damage at the early stage of focal cerebral ischemia through the regulation of TJ and PKCasignaling.
This points towards progranulin as a potent neuroprotective agent against mutant huntingtin neurodegeneration," Dr.
Lead researcher Dr Xiang Gao, from the Harvard School of Public Health in Boston, Massachusetts, said: "Our findings suggest that ibuprofen could be a potential neuroprotective agent against Parkinson's disease, however the exact mechanism is unknown.
The promising results of the trial suggest that further investigation into the extract as a neuroprotective agent is warranted.
Such a long interval brings the hope that if a "mysterious and magical neuroprotective agent is identified," Schenck says, it could be used before brain damage is severe.
However, results of the recent PREMAG trial, evaluating whether a single infusion of magnesium sulfate given to mothers would be neuroprotective in preterm newborns, were inconclusive (BJOG 2007;114:310-8), and a Cochrane Review concluded that the role for "antenatal magnesium sulfate therapy as a neuroprotective agent for the preterm fetus is not yet established" (Cochrane Database Syst.
This trial will enroll 5,000 acute stroke patients to evaluate the efficacy of diazepam (Valium) as a GABA agonist type of neuroprotective agent (Lodder).
DP-b99, D-Pharm's neuroprotective agent for stroke recently successfully completed of the first stage of an ongoing Phase I safety assessment.
paramedics will start administering magnesium - a neuroprotective agent - to stroke victims via an intravenous line.
Although a few reviews published previously have described the multifaceted efficacy of melatonin against MPTP and 6-OHDA rodent models, due to development and validation of the newer models as well as the extensive studies on the usage of melatonin in entrenched PD models, it is worthwhile to bring up to date note on the usage of melatonin as a neuroprotective agent in PD.
Future hopes In stroke care focus on a combination of a thrombolytic and a neuroprotective agent for better recovery.