neuroprotective agent

Neurology Any agent or drug that protects the brain from secondary injury caused by stroke. See Stroke.

References in periodicals archive ?

In conclusion, ginsenoside Rg1 as a ginsenoside neuroprotective agent could improve neurological injury, attenuate blood brain barrier disruption and downregulate aquaporin 4 expression induced by cerebral ischemia/reperfusion insults in rats.

Ginsenoside Rg1 provides neuroprotection against blood brain barrier disruption and neurological injury in a rat model of cerebral ischemia/reperfusion through downregulation of aquaporin 4 expression

These results demonstrate that GTPs may act as a potential neuroprotective agent against BBB damage at the early stage of focal cerebral ischemia through the regulation of TJ and PKCasignaling.

Green tea polyphenols alleviate early blood brain barrier damage during experimental focal cerebral ischemia through regulating tight junctions and PKCalpha signalling

This points towards progranulin as a potent neuroprotective agent against mutant huntingtin neurodegeneration," Dr.

Chemical 'switches' for neurodegenerative diseases identified

Lead researcher Dr Xiang Gao, from the Harvard School of Public Health in Boston, Massachusetts, said: "Our findings suggest that ibuprofen could be a potential neuroprotective agent against Parkinson's disease, however the exact mechanism is unknown.

Painkiller 'protects against Par kinson's' Ibuprofen may slow progress of the disease

The promising results of the trial suggest that further investigation into the extract as a neuroprotective agent is warranted.

Silymarin neuroprotective effects

Such a long interval brings the hope that if a "mysterious and magical neuroprotective agent is identified," Schenck says, it could be used before brain damage is severe.

Young man's dreams, old man's fate: disorder can presage neurodegenerative disease by decades

However, results of the recent PREMAG trial, evaluating whether a single infusion of magnesium sulfate given to mothers would be neuroprotective in preterm newborns, were inconclusive (BJOG 2007;114:310-8), and a Cochrane Review concluded that the role for "antenatal magnesium sulfate therapy as a neuroprotective agent for the preterm fetus is not yet established" (Cochrane Database Syst.

Magnesium sulfate in pregnancy cuts CP in preemies: risk of death at 2 years did not decrease

This trial will enroll 5,000 acute stroke patients to evaluate the efficacy of diazepam (Valium) as a GABA agonist type of neuroprotective agent (Lodder).

Neuroprotection for ischemic stroke. (Pharmacology Update)

DP-b99, D-Pharm's neuroprotective agent for stroke recently successfully completed of the first stage of an ongoing Phase I safety assessment.

D-Pharm receives prodrug technology patent

paramedics will start administering magnesium - a neuroprotective agent - to stroke victims via an intravenous line.

TIMING IS OF THE ESSENCE UCLA TRIES TO HURRY AID FOR STROKES

Although a few reviews published previously have described the multifaceted efficacy of melatonin against MPTP and 6-OHDA rodent models, due to development and validation of the newer models as well as the extensive studies on the usage of melatonin in entrenched PD models, it is worthwhile to bring up to date note on the usage of melatonin as a neuroprotective agent in PD.

Melatonin as a neuroprotective agent in the rodent models of Parkinson's disease: is it all set to irrefutable clinical translation?

Future hopes In stroke care focus on a combination of a thrombolytic and a neuroprotective agent for better recovery.