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the ability to exert a destructive or poisonous effect upon nerve tissue. adj., adj neurotox´ic.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
However, the researchers said there is a need for a rigorously designed, larger clinical trial for a continued investigation into the potentiality of neuroprotective effects of polyphenols, which is abundant in pomegranate juice.
The publication entitled, "Effects of Varying Intranasal Treatment Regimens in ST266-Mediated Retinal Ganglion Cell Neuroprotection," details the preclinical study exploring the neuroprotective effects of daily and twice daily intranasally delivered ST266 to evaluate different treatment regimens an EAE-induced experimental ON mouse model.
Although the exact mechanism behind the neuroprotective effects of Hsd remains unclear, it is likely to demonstrate both antioxidant and calcium blocking properties.
Recently, there was also significant evidence indicating that gastrodin elicited strong neuroprotective effects against loss of retinal ganglion cells in an acute glaucoma rat via inhibiting phosphorylated p38 MAPK and the production of proinflammatory mediators in activated retinal microglia.
UCLA researchers proposed that molecular mechanisms behind each disability may differ, and that neuroprotective treatments tailored for each disability may be more effective than nonspecific treatments aiming to reduce a composite of different disabilities.
Tea contains antioxidants and anti-inflammatory and neuroprotective chemicals, which have been associated with a lowered risk of serious conditions, including heart disease, cancer and diabetes, the researchers said.
Previous studies conducted with neurotoxic agents have demonstrated the neuroprotective effect of selenium on the central and peripheral nervous systems (8,13-16).
Until now, many researchers have attempted to find neuroprotective actions of medical plants and their components and studied their mechanisms of ischemia-induced neuronal death, such as glutamate-induced excitotoxicity, oxidative stress by excessive production of reactive oxygen species (ROS), and glial activation-mediated inflammatory response.[sup][7],[8],[9],[10],[11]
The current study was aimed to observe the neuroprotective effect of metformin against PTZ-induced apoptotic neurodegeneration in human cortical neuronal cell culture.
G-CSF exerts neuroprotective actions through the inhibition of apoptosis and inflammation, and the stimulation of neurogenesis.
At present, lots of studies focus on exploring antiinflammatory and neuroprotective agents that may alleviate cerebral I/R injury.