neuroprotection


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neuroprotection

[noo͡r′ō·prō·tek′shən]
protection against neurotoxicity.

neuroprotection

(nūr″ō-prō-tĕk′shŭn)
The science of minimizing secondary neurologic damage following stroke or trauma. Certain drugs, enzymes, hormones, and physical actions, such as inducing hypothermia, may act as neuroprotectors.

neuroprotection

A therapeutic strategy aimed at preventing the ultimate result of a neurodegenerative disease process. Example: in current glaucoma therapy, the principal objective is to lower the intraocular pressure, but that appears to be only one of the risk factors that lead ultimately to shrinkage and/or death of retinal ganglion cells and visual field loss. Visual field losses occur even after the intraocular pressure is returned to within the normal range in some patients. Neuroprotection is aimed at preventing that secondary ganglion cell degeneration in glaucomatous eyes, which may have been caused as a result of inflammatory or toxic mediators released by the primary degenerative event. Neuroprotective strategies presently being evaluated include glutamate antagonists, calcium channel blockers, nitric oxide synthase inhibitors and neurotrophins.
References in periodicals archive ?
This report describes the role of neuroprotection in acute disorders such as stroke and injuries of the nervous system as well as in chronic diseases such as neurodegenerative disorders because many of the underlying mechanisms of damage to neural tissues are similar in all these conditions and several products are used in more than one disorder.
com)-- Confirming its investment in the area of brain inflammation and neuroprotection, CreAgri welcomes German University of Darmstadt's announcement on the launch of the research project NeurOliv with the support of the German government.
range required for endovascular surgery included 26 groups of products, including stents, catheters, stentgrafts kits thrombolysis, torqery, Y connectors, ramps, t-shirts, guides and Lock vascular filters, introducers, extension cords, high pressure mikrocewniki syringe pressure systems, neuroprotection, systems for the removal of foreign bodies from the blood vessels, blood thrombectomy kits, threads, vascular grafts, vascular patches.
The Oxford University research group have now identified the first example of the brain having its own built-in form of neuroprotection, so-called 'endogenous neuroprotection'.
Hormones in neurodegeneration, neuroprotection, and neurogenesis.
The neuroprotection effect of pretreatment with olive leaf extract on brain lipidomics in rat stroke model.
The purposes of this study were to determine whether carnosine is neuroprotective in permanent focal cerebral ischemia and to determine potential mechanisms of neuroprotection.
Some specific topics examined include the impact of intracellular A-beta amyloid peptide in health and disease, the role of LIMK1 in neuronal degeneration in Alzheimer's disease, the multiple regulatory mechanisms of neuroprotection by astrocytes, and glycogen synthase kinase 3 as a molecular target for Alzheimer's disease and other tauopathies.
Neuroprotection is a process by which neuronal function is shielded from injury or is restored following injury.
According to a recent study, COPAXONE(R) stimulates T-cells to produce the neuroprotection factor BDNF (brain-derived neurotrophic factor) in tissue culture using T-cells from a COPAXONE(R) patient.
With the approval of new products and takeover of markets for obsolete symptomatic therapies, the neuroprotection market value will rise by the year 2017 when it will constitute a major and important component of the CNS market.
ROADSTER 2 is a prospective, multi-center study designed to assess the real world treatment of patients at risk for stroke due to carotid artery disease with the recently FDA-approved ENROUTE Transcarotid Neuroprotection (NPS) and Stent System, the first devices designed specifically for TCAR -- TransCarotid Artery Revascularization.