Evaluation of the good tumor response of embryonal tumor with abundant neuropil
and true rosettes.
The remodeling of the neuropil
induced by ICH is as described in (b).
Here, it is also likely that the position of the guide cannula for the microinjection let the substances spread from the medial border of the MePD through its neuropil
, and the coarse axons of the optic tract, situated in the back of the microinjection site, might have limited drug diffusion outside the MePD.
Aggregates of abnormally hyperphosphorylated MAPT are the main constituent of neurofibrillary tangles (NFTs) and neuropil
threads (NTs) that are characteristic neuropathological hallmark lesions of Alzheimer's disease (AD) [17, 18].
(8) As the connections between neurons (the neuropil
) are progressively lost in the aging brain, so are memory, sensory learning, and neuroplasticity.
[9,16] The increase in volume noted in the nucleus ovoidalis in the auditory stimulated groups could be due to the observed increase in its neuronal number as well as changes in the neuropil
. The changes in the neuropil
can be further determined by studying the dendritic and axonal profiles of the nucleus ovoidalis.
When tau is hyperphosphorylated, primarily by the action of serine/threonine kinases, it dissociates from microtubules, leading to the formation of paired helical fragments that, in turn, aggregate into neurofibrillary tangles and neuropil
 Braak and Braak  proposed a predictive model of the progressive stages of AD based on the distribution of neurofibrillary tangles (NFT) and neuropil
threads found in brain autopsies.
The monkeys that received a higher dose and died at 67 and 132 DPI showed marked liquefactive necrosis of the cerebrum with formation of variable sized irregular cystic cavities lined by atrophied parenchymal septa, containing remnants of neuropil
(Figure 3) and chronic inflammatory cells, predominantly fibroblasts.
Histopathologically, while most prion diseases, including CJD, BSE, CWD, and most of scrapie cases (i.e., the classic transmissible spongiform encephalopathies or TSEs), are characterized by the triad of spongiform change, gliosis, and neuronal loss, some rare but very informative variants such as FI, GSS, or PrP-CAA may show very subtle or even absent spongiform change or be characterized by prominent extracellular amyloid plaques accumulating either in the neuropil
or around blood vessels.
Treatment-responsive limbic encephalitis identified by neuropil
antibodies: MPJ and PET correlates.
The generalized histopathology reveals spongiform degeneration in the neuropil
of the brain and spinal cord.