The structure of the preprovasopressin with the main constituent domains: Signal peptide, AVP, neurophysin
II and copeptin (aa, aminoacid position; AVP, arginine vasopressin)
A novel mutation in the coding region for neurophysin II is associated with autosomal dominant neurohypophyseal diabetes insipidus.
Heterologous expression of human vasopressin neurophysin precursors in a pituitary cell line: defective transport of mutant protein from patients with familial diabetes insipidus.
Autosomal dominant neurohypophyseal diabetes insipidus associated with a missense mutation encoding Gly23-Val in neurophysin II.
A de novo mutation in the coding sequence for neurophysin II (Pro24-Leu) is associated with onset and transmission of autosomal dominant neurohypophyseal diabetes insipidus.
A single base substitution in the coding region for neurophysin II associated with familial central diabetes insipidus.