neurophysin

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neurophysin

[noor″o-fi´sin]

any of a group of soluble proteins secreted in the hypothalamus that serve as binding proteins for vasopressin and oxytocin, playing a role in their transport in the neurohypophyseal tract and their storage in the posterior pituitary.

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neurophysins

References in periodicals archive ?

The structure of the preprovasopressin with the main constituent domains: Signal peptide, AVP, neurophysin II and copeptin (aa, aminoacid position; AVP, arginine vasopressin)

Endocrine dysfunction in sepsis: a beneficial or deleterious host response?

Biosynthesis of vasopressin and neurophysins. In: Gash D, Boer G, eds.

Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin

A novel mutation in the coding region for neurophysin II is associated with autosomal dominant neurohypophyseal diabetes insipidus.

Heterologous expression of human vasopressin neurophysin precursors in a pituitary cell line: defective transport of mutant protein from patients with familial diabetes insipidus.

Autosomal dominant neurohypophyseal diabetes insipidus associated with a missense mutation encoding Gly23-Val in neurophysin II.

A de novo mutation in the coding sequence for neurophysin II (Pro24-Leu) is associated with onset and transmission of autosomal dominant neurohypophyseal diabetes insipidus.

A single base substitution in the coding region for neurophysin II associated with familial central diabetes insipidus.

Identification of two distinct mutations at the same nucleotide position, concomitantly with a novel polymorphism in the vasopressin-neurophysin II gene (AVP-NP II) in two Dutch families with familial neurohypophyseal diabetes insipidus

Vasopressin and its neurophysin. In: DeGroot U, ed.

Improved extraction procedure and RIA for determination of [arginine.sup.8]-vasopressin in plasma: role of premeasurement sample treatment and reference values in children