Neuronal nitric oxide synthase within paraventricular nucleus: blood pressure and baroreflex in two-kidney, one-clip hypertensive rats.
Rat basal forebrain cholinergic lesion affects
neuronal nitric oxide synthase activity in hippocampal and neocortical target regions.
Lack of phencyclidine-induced effects in mice with reduced
neuronal nitric oxide synthase. Psychopharmacology (Berl), 155, 299-309.
Thiols and
neuronal nitric oxide synthase: complex formation, competitive inhibition and enzyme stabilization.
Abbreviations: CNS, central nervous system; cDNA, complementary DNA; 5-HT, serotonin; NO, nitric oxide; NOS, nitric oxide synthase; nNOS,
neuronal nitric oxide synthase; RT-PCR, reverse transcription based-polymerase chain reaction.
Other topics include manipulation of
neuronal nitric oxide synthase, examination of stem cells in post-ischemic and transplanted hearts, and detection of apoptosis in cardiovascular disease.
Excessive activation of N-methyl-D-aspartate receptors (NMDARs) and subsequent production of nitric oxide by
neuronal nitric oxide synthase (nNOS) contribute to neuronal damage resulting from hypoxic and ischemic insults.
Hall et al., "Structural organization of the human
neuronal nitric oxide synthase gene (NOS1)," The Journal of Biological Chemistry, vol.
Genetic knockout and pharmacologic inhibition of
neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice.
Tao, "Genetic knockout and pharmacologic inhibition of
neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice," Molecular Pain, vol.
NO is also produced by the neurons where
neuronal nitric oxide synthase (nNOS/ NOS1), another constitutive enzyme, is responsible for its production.
Pharmacokinetics and protein binding of the selective
neuronal nitric oxide synthase inhibitor 7-nitroindazole.