neuronal nitric oxide synthase


Also found in: Acronyms.

neuronal nitric oxide synthase

the constitutive isoform of nitric oxide synthase found within neurons.
See also: nitric oxide synthase, nitric oxide.
Farlex Partner Medical Dictionary © Farlex 2012

neuronal nitric oxide synthase

See nNOS.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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References in periodicals archive ?
Neuronal nitric oxide synthase within paraventricular nucleus: blood pressure and baroreflex in two-kidney, one-clip hypertensive rats.
Rat basal forebrain cholinergic lesion affects neuronal nitric oxide synthase activity in hippocampal and neocortical target regions.
Lack of phencyclidine-induced effects in mice with reduced neuronal nitric oxide synthase. Psychopharmacology (Berl), 155, 299-309.
Thiols and neuronal nitric oxide synthase: complex formation, competitive inhibition and enzyme stabilization.
Abbreviations: CNS, central nervous system; cDNA, complementary DNA; 5-HT, serotonin; NO, nitric oxide; NOS, nitric oxide synthase; nNOS, neuronal nitric oxide synthase; RT-PCR, reverse transcription based-polymerase chain reaction.
Other topics include manipulation of neuronal nitric oxide synthase, examination of stem cells in post-ischemic and transplanted hearts, and detection of apoptosis in cardiovascular disease.
Excessive activation of N-methyl-D-aspartate receptors (NMDARs) and subsequent production of nitric oxide by neuronal nitric oxide synthase (nNOS) contribute to neuronal damage resulting from hypoxic and ischemic insults.
Hall et al., "Structural organization of the human neuronal nitric oxide synthase gene (NOS1)," The Journal of Biological Chemistry, vol.
Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice.
Tao, "Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice," Molecular Pain, vol.
NO is also produced by the neurons where neuronal nitric oxide synthase (nNOS/ NOS1), another constitutive enzyme, is responsible for its production.
Pharmacokinetics and protein binding of the selective neuronal nitric oxide synthase inhibitor 7-nitroindazole.

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