neuromyelitis optica

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inflammation of nervous and medullary substance; myelitis attended with neuritis.
neuromyelitis op´tica combined demyelination of the optic nerve and spinal cord, with diminution of vision and possible blindness, flaccid paralysis of extremities, and sensory and genitourinary disturbances.

neu·ro·my·e·li·tis op·'ti·ca

a demyelinating disorder consisting of a transverse myelopathy and optic neuritis.
Synonym(s): Devic disease

neu·ro·my·e·li·tis op·ti·ca

(nūr'ō-mī-ĕ-lī'tis op'tik-ă)
A demyelinating disorder consisting of a transverse myelopathy and optic neuritis.
Synonym(s): Devic disease.

neuromyelitis optica

An acute nervous system disorder featuring DEMYELINATION of the tracts in the nerve tracts in the spinal cord and both optic nerves. The condition occurs about a week after an attack of measles or chickenpox or may follow vaccination. There is headache, vomiting, stiff neck, paralysis and blindness and the death rate is high. In those who survive, recovery is often surprisingly complete. Also known as Devic's disease. (Eugene Devic, 1858–1930, French physician).


Eugène, French physician, 1869-1930.
Devic disease - a demyelinating disorder consisting of a transverse myelopathy and optic neuritis. Synonym(s): neuromyelitis optica
References in periodicals archive ?
Wingerchuk DM, Lucchinetti CF Comparative immunopathogenesis of acute disseminated encephalomyelitis, neuromyelitis optica, and multiple sclerosis.
About Neuromyelitis Optica Because NMO has only recently been identified as a syndrome distinct from MS, it is difficult to know how many people have it.
22, 2015 /PRNewswire-iReach/ -- The report " Neuromyelitis Optica (Devic's Syndrome) -- Pipeline Review, H1 2015" provides comprehensive information on the therapeutic development for Neuromyelitis Optica (Devic's Syndrome), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
Neuromyelitis Optica Spectrum Disorder as an Initial Presentation of Primary Sjogren's Syndrome.
Absence of aquaporin-4 expression in lesions of neuromyelitis optica but increased expression in multiple sclerosis lesions and normal-appearing white matter.
The NMO Roundtable Conference, entitled "A Rare Approach to A Rare Disease," is focused on a cure for neuromyelitis optica (NMO) spectrum disease, a rare disorder often misdiagnosed as multiple sclerosis.
An extensive serological testing for neurophilic viruses, systemic vasculitis markers and neuromyelitis optica (NMO) IgG were negative.
Neuromyelitis optica (NMO), also traditionally considered an MS variant, is differentiated by: unique imaging, cerebrospinal fluid (CSF) findings and neuropathology; a relatively strong association with autoimmune disease; and a favourable response to plasma exchange.
12 Methotrexate is Highly Effective for the Treatment of Neuromyelitis Optica Spectrum Disorders
Robert Axtell, assistant member at the Oklahoma Medical Research Foundation (United States), received a grant to examine the role of inflammation-inducing cell signaling molecules called BAFF and APRIL in two different animal models of neuro-inflammation, one that mimics MS and another that mimics neuromyelitis optica.
The second topic of the morning session dealt with the controversy about whether neuromyelitis optica (NMO) is a distinct disease entity from MS with B Weinshenker (USA) arguing the affirmative and A Compston (UK) arguing the negative.