floppy infant(redirected from neuromuscular junction disease)
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floppy infantFloppy infant syndrome Neonatology A neonate with poor muscle tone and/or response to stimulation of extremities caused by a heterogeneous group of neuromuscular and musculoskeletal disorders
Floppy infant causes
Bone disease Osteogenesis imperfecta, rickets
CNS Atonic diplegia, cerebellar ataxia, cerebral lipidosis, chromosome defects, kernicterus, Lowe's oculocerebrorenal syndrome, Prader-Willi syndrome, Zellweger cerebrohepatocellular syndrome
Muscle disease Central core disease, glycogen storage disease type IIa–Pompe's disease, mitochondrial myopathies, muscular dystrophy, myotonic dystrophy, nemaline myopathy
Neuromuscular junction disease Botulism, myasthenia gravis
Peripheral nerve disease Amyotonia congenita, anterior horn cell disease, congenital sensory neuropathy, familial dysautonomia, Guillain-Barré syndrome, polyneuritis
Spinal cord disease Poliomyelitis, spinal cord trauma and tumors, transverse myelopathy, Werdnig-Hoffmann disease
Non-neuromuscular disease Endocrinopathies, metabolic disease, vitamin deficiency
flop·py in·fant(flop'ē in'fănt)
A young child afflicted with neuromuscular or muscular disorders such that the limbs cannot move independently.