When a non-depolarising neuromuscular blocking drug
is preceded by the same or another sub-paralysing dose of non-depolarising muscle relaxant, there is shorter onset of neuromuscular blockade.
The use of a nerve stimulator is strongly recommended to monitor the effect of neuromuscular blocking drugs
during intraoperative hypothermia.
The present study demonstrated that a bolus dose of remifentanil given simultaneously with sevoflurane and nitrous oxide produced acceptable intubating conditions at two minutes in healthy premedicated paediatric patients without the use of neuromuscular blocking drugs
Literature findings on the presence of anti-AChR antibodies and sensitivity to nondepolarizing neuromuscular blocking drugs
in myasthenic patients undergoing cardiac surgery with CPB are inconsistent.
Postoperative residual block after intermediate-acting neuromuscular blocking drugs
. Anaesthesia 2001; 56:312-318.
(69) In 2006, the ASA commissioned a task force on the subject, and eventually issued a lengthy practice advisory intended to "reduce the frequency of unintended intraoperative awareness." (70) Among other things, the report warned that the "use of neuromuscular blocking drugs
[such as pancuronium] may mask purposeful or reflex movements and adds additional importance to the use of monitoring methods that assure the adequate delivery of anesthesia." (71)
Intended to serve as a quick resource for information about the pharmacology of drugs encountered during anesthesia and to the physiologic responses that impact anesthetics, this guide covers inhaled anesthetics, opiod agonists and antagonists, barbituates, local anesthetics, neuromuscular blocking drugs
, digitalis and related drugs, calcium channel blockers, and anti-hypertensive drugs, among others, as well as cell structure and function, body fluids, autonomic nervous systems, pain, acid-base balance, and metabolism, among other topics.
Simple high-performance liquid chromatographic method for the analysis of the non-depolarizing neuromuscular blocking drugs
in clinical anaesthesia.
Thus, anesthetic and neuromuscular blocking drugs
, analgesics, preparations for eye surgery, specialized antibiotics, immunosuppressant, and some chemotherapeutic and highly specialized drugs are not provided through PBS.